GO Annotations Graph

• Symbol: Nppc
• Name: natriuretic peptide type C
• ID: MGI:97369

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005179	hormone activity	ISO	J:155856
Molecular Function	GO:0005179	hormone activity	IBA	J:265628
Molecular Function	GO:0051427	hormone receptor binding	ISO	J:164563
Molecular Function	GO:0051427	hormone receptor binding	IBA	J:265628
Molecular Function	GO:0005184	neuropeptide hormone activity	TAS	J:36239
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IDA	J:86794
Cellular Component	GO:0005576	extracellular region	TAS	J:21913
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0030141	secretory granule	ISO	J:155856
Biological Process	GO:0001525	angiogenesis	IMP	J:287812
Biological Process	GO:0001525	angiogenesis	IMP	J:287812
Biological Process	GO:0048513	animal organ development	IMP	J:122924
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:287812
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:287812
Biological Process	GO:0061939	c-di-GMP signaling	IDA	J:192266
Biological Process	GO:1904588	cellular response to glycoprotein	IDA	J:190645
Biological Process	GO:0006182	cGMP biosynthetic process	IMP	J:75620
Biological Process	GO:0006182	cGMP biosynthetic process	ISO	J:164563
Biological Process	GO:0006182	cGMP biosynthetic process	IBA	J:265628
Biological Process	GO:0019934	cGMP-mediated signaling	ISO	J:155856
Biological Process	GO:0051276	chromosome organization	IMP	J:191608
Biological Process	GO:0001549	cumulus cell differentiation	IMP	J:191608
Biological Process	GO:0035483	gastric emptying	IDA	J:192266
Biological Process	GO:0003418	growth plate cartilage chondrocyte differentiation	IMP	J:75620
Biological Process	GO:0003419	growth plate cartilage chondrocyte proliferation	IMP	J:75620
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IDA	J:275270
Biological Process	GO:0051321	meiotic cell cycle	IMP	J:164870
Biological Process	GO:1903537	meiotic cell cycle process involved in oocyte maturation	IMP	J:191608
Biological Process	GO:0071965	multicellular organismal locomotion	IMP	J:269662
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	ISO	J:155856
Biological Process	GO:2000279	negative regulation of DNA biosynthetic process	ISO	J:155856
Biological Process	GO:0051447	negative regulation of meiotic cell cycle	IMP	J:164870
Biological Process	GO:0051447	negative regulation of meiotic cell cycle	ISO	J:73065
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:269662
Biological Process	GO:1900194	negative regulation of oocyte maturation	IMP	J:164870
Biological Process	GO:1900194	negative regulation of oocyte maturation	ISO	J:73065
Biological Process	GO:0048599	oocyte development	IMP	J:191608
Biological Process	GO:0001503	ossification	IEA	J:60000
Biological Process	GO:0001541	ovarian follicle development	IMP	J:191608
Biological Process	GO:0010753	positive regulation of cGMP-mediated signaling	ISO	J:155856
Biological Process	GO:0043306	positive regulation of mast cell degranulation	ISO	J:155856
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:155856
Biological Process	GO:1900721	positive regulation of uterine smooth muscle relaxation	ISO	J:155856
Biological Process	GO:0009791	post-embryonic development	IMP	J:122924
Biological Process	GO:0006457	protein folding	ISO	J:164563
Biological Process	GO:0007168	receptor guanylyl cyclase signaling pathway	ISO	J:164563
Biological Process	GO:0007168	receptor guanylyl cyclase signaling pathway	IBA	J:265628
Biological Process	GO:0007168	receptor guanylyl cyclase signaling pathway	ISO	J:73065
Biological Process	GO:0040014	regulation of multicellular organism growth	IMP	J:122924
Biological Process	GO:0022414	reproductive process	IMP	J:164870
Biological Process	GO:0048678	response to axon injury	IMP	J:269662
Biological Process	GO:0036293	response to decreased oxygen levels	IMP	J:269662
Biological Process	GO:0002931	response to ischemia	IMP	J:287812
Biological Process	GO:0002931	response to ischemia	IMP	J:287812
Biological Process	GO:0090649	response to oxygen-glucose deprivation	IMP	J:269662
Biological Process	GO:0009611	response to wounding	IMP	J:269662
Biological Process	GO:0009611	response to wounding	IMP	J:269662