Ascl1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ascl1
achaete-scute family bHLH transcription factor 1
MGI:96919

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:197142
Molecular Function	GO:0003682	chromatin binding	IDA	J:197142
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:241054
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:119653
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0003676	nucleic acid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:197142
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:119653
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	IDA	J:109287
Cellular Component	GO:0043025	neuronal cell body	IDA	J:67408
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:79854
Cellular Component	GO:0005634	nucleus	IDA	J:64088
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	IDA	J:64088
Cellular Component	GO:0005634	nucleus	IDA	J:64088
Cellular Component	GO:0005634	nucleus	IDA	J:2319
Cellular Component	GO:0005634	nucleus	IDA	J:64088
Cellular Component	GO:0005634	nucleus	IDA	J:64088
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IBA	J:265628
Biological Process	GO:0061104	adrenal chromaffin cell differentiation	IMP	J:79390
Biological Process	GO:0061103	carotid body glomus cell differentiation	IMP	J:99328
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0048469	cell maturation	IMP	J:174488
Biological Process	GO:0021954	central nervous system neuron development	IMP	J:110059
Biological Process	GO:0021954	central nervous system neuron development	IGI	J:105524
Biological Process	GO:0021987	cerebral cortex development	IMP	J:132162
Biological Process	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	IMP	J:188110
Biological Process	GO:0048484	enteric nervous system development	TAS	J:55391
Biological Process	GO:0021879	forebrain neuron differentiation	ISO	J:155856
Biological Process	GO:0097154	GABAergic neuron differentiation	IGI	J:90073
Biological Process	GO:0048699	generation of neurons	IMP	J:196947
Biological Process	GO:0061100	lung neuroendocrine cell differentiation	IMP	J:113000
Biological Process	GO:0097475	motor neuron migration	IGI	J:99297
Biological Process	GO:0097475	motor neuron migration	IMP	J:99297
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0050883	musculoskeletal movement, spinal reflex action	IMP	J:196947
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IDA	J:241054
Biological Process	GO:0007399	nervous system development	ISO	J:155856
Biological Process	GO:0061351	neural precursor cell proliferation	IMP	J:171415
Biological Process	GO:0007400	neuroblast fate determination	IMP	J:65410
Biological Process	GO:0007400	neuroblast fate determination	IMP	J:79854
Biological Process	GO:0007405	neuroblast proliferation	IGI	J:99297
Biological Process	GO:0061101	neuroendocrine cell differentiation	IMP	J:64088
Biological Process	GO:0022008	neurogenesis	ISO	J:164563
Biological Process	GO:0048666	neuron development	IDA	J:241054
Biological Process	GO:0048666	neuron development	IMP	J:40190
Biological Process	GO:0030182	neuron differentiation	IDA	J:241054
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0030182	neuron differentiation	IMP	J:110059
Biological Process	GO:0030182	neuron differentiation	IMP	J:91076
Biological Process	GO:0030182	neuron differentiation	IDA	J:133461
Biological Process	GO:0048663	neuron fate commitment	IDA	J:241054
Biological Process	GO:0048663	neuron fate commitment	IGI	J:100187
Biological Process	GO:0048663	neuron fate commitment	IMP	J:110261
Biological Process	GO:0048663	neuron fate commitment	IMP	J:151457
Biological Process	GO:0048663	neuron fate commitment	IMP	J:82270
Biological Process	GO:0048665	neuron fate specification	IDA	J:241054
Biological Process	GO:0048665	neuron fate specification	IMP	J:110059
Biological Process	GO:0003358	noradrenergic neuron development	IMP	J:130853
Biological Process	GO:0003359	noradrenergic neuron fate commitment	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:99297
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:110291
Biological Process	GO:0060166	olfactory pit development	IMP	J:40190
Biological Process	GO:0021779	oligodendrocyte cell fate commitment	IMP	J:132162
Biological Process	GO:0014003	oligodendrocyte development	IMP	J:135661
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:135661
Biological Process	GO:0048709	oligodendrocyte differentiation	IGI	J:99297
Biological Process	GO:0048486	parasympathetic nervous system development	TAS	J:55391
Biological Process	GO:0007389	pattern specification process	IMP	J:98802
Biological Process	GO:0048935	peripheral nervous system neuron development	IMP	J:30246
Biological Process	GO:0045787	positive regulation of cell cycle	IDA	J:171415
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	IMP	J:171415
Biological Process	GO:0050769	positive regulation of neurogenesis	IMP	J:110059
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:110059
Biological Process	GO:0045666	positive regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IMP	J:110291
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36282
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36282
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:119653
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36282
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:197573
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:119653
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:197573
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:119653
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:197573
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36282
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:197142
Biological Process	GO:0042127	regulation of cell population proliferation	IDA	J:153961
Biological Process	GO:0030856	regulation of epithelial cell differentiation	IMP	J:195630
Biological Process	GO:0010468	regulation of gene expression	IMP	J:130853
Biological Process	GO:0010468	regulation of gene expression	IMP	J:135661
Biological Process	GO:0010468	regulation of gene expression	IMP	J:135661
Biological Process	GO:0010468	regulation of gene expression	IMP	J:110059
Biological Process	GO:0010468	regulation of gene expression	IMP	J:110059
Biological Process	GO:0007346	regulation of mitotic cell cycle	IMP	J:188110
Biological Process	GO:0050767	regulation of neurogenesis	IBA	J:265628
Biological Process	GO:0050767	regulation of neurogenesis	IMP	J:160260
Biological Process	GO:0050767	regulation of neurogenesis	IMP	J:188110
Biological Process	GO:0008593	regulation of Notch signaling pathway	IMP	J:151457
Biological Process	GO:0060165	regulation of timing of subpallium neuron differentiation	IMP	J:51598
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:241054
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:154112
Biological Process	GO:0007423	sensory organ development	IBA	J:265628
Biological Process	GO:0021527	spinal cord association neuron differentiation	IMP	J:110261
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	IGI	J:135661
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	IGI	J:135661
Biological Process	GO:0021530	spinal cord oligodendrocyte cell fate specification	IMP	J:135661
Biological Process	GO:0061102	stomach neuroendocrine cell differentiation	IMP	J:138261
Biological Process	GO:0060163	subpallium neuron fate commitment	IMP	J:51598
Biological Process	GO:0061549	sympathetic ganglion development	IMP	J:130853
Biological Process	GO:0048485	sympathetic nervous system development	TAS	J:55391
Biological Process	GO:0060579	ventral spinal cord interneuron fate commitment	IMP	J:100187
Biological Process	GO:0021750	vestibular nucleus development	IMP	J:107718

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