GO Annotations Graph

• Symbol: Hgf
• Name: hepatocyte growth factor
• ID: MGI:96079

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042056	chemoattractant activity	ISO	J:164563
Molecular Function	GO:0008083	growth factor activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:248279
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0004252	serine-type endopeptidase activity	IEA	J:72247
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-1266699
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0060326	cell chemotaxis	ISO	J:164563
Biological Process	GO:0000902	cell morphogenesis	IDA	J:78319
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	ISO	J:164563
Biological Process	GO:0050673	epithelial cell proliferation	IDA	J:78319
Biological Process	GO:0050673	epithelial cell proliferation	IDA	J:92782
Biological Process	GO:0048012	hepatocyte growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0048012	hepatocyte growth factor receptor signaling pathway	IBA	J:265628
Biological Process	GO:0048012	hepatocyte growth factor receptor signaling pathway	IDA	J:92782
Biological Process	GO:0001889	liver development	IDA	J:111404
Biological Process	GO:0051450	myoblast proliferation	IDA	J:106496
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	IDA	J:92782
Biological Process	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IDA	J:166840
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IDA	J:166840
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	IDA	J:166840
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:155856
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	ISO	J:164563
Biological Process	GO:0032733	positive regulation of interleukin-10 production	IDA	J:166840
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:92782
Biological Process	GO:0031643	positive regulation of myelination	ISO	J:155856
Biological Process	GO:0070572	positive regulation of neuron projection regeneration	ISO	J:155856
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IBA	J:265628
Biological Process	GO:0006508	proteolysis	IEA	J:72247
Biological Process	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	IMP	J:85916
Biological Process	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	ISO	J:73065
Biological Process	GO:1900744	regulation of p38MAPK cascade	IDA	J:204089
Biological Process	GO:1902947	regulation of tau-protein kinase activity	IDA	J:166840
Biological Process	GO:0014856	skeletal muscle cell proliferation	IDA	J:106496