GO Annotations Graph

• Symbol: Grid2
• Name: glutamate receptor, ionotropic, delta 2
• ID: MGI:95813

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008066	glutamate receptor activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	IEA	J:72247
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0030165	PDZ domain binding	IPI	J:150922
Molecular Function	GO:0005515	protein binding	IPI	J:150922
Molecular Function	GO:0005515	protein binding	IPI	J:165995
Molecular Function	GO:0005515	protein binding	IPI	J:269669
Molecular Function	GO:0005515	protein binding	IPI	J:101279
Molecular Function	GO:0005515	protein binding	IPI	J:101279
Molecular Function	GO:0005515	protein binding	IPI	J:78719
Molecular Function	GO:0005515	protein binding	IPI	J:74533
Molecular Function	GO:0005515	protein binding	IPI	J:150695
Molecular Function	GO:0005515	protein binding	IPI	J:74533
Molecular Function	GO:0005515	protein binding	IPI	J:150695
Molecular Function	GO:0097110	scaffold protein binding	IPI	J:150922
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IBA	J:265628
Cellular Component	GO:0043197	dendritic spine	IDA	J:150922
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:159100
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:159100
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:159100
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:159100
Cellular Component	GO:0008328	ionotropic glutamate receptor complex	IDA	J:150922
Cellular Component	GO:0016020	membrane	IDA	J:101279
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	ISO	J:155856
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	IDA	J:159100
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	IDA	J:159100
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	IMP	J:159100
Cellular Component	GO:0005886	plasma membrane	IDA	J:150922
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	IBA	J:265628
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:159100
Cellular Component	GO:0098839	postsynaptic density membrane	IMP	J:159100
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:159100
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:150922
Cellular Component	GO:0036477	somatodendritic compartment	IDA	J:135974
Cellular Component	GO:0045202	synapse	IDA	J:78719
Cellular Component	GO:0045202	synapse	IDA	J:136382
Biological Process	GO:0021707	cerebellar granule cell differentiation	IGI	J:165995
Biological Process	GO:0060079	excitatory postsynaptic potential	IMP	J:24477
Biological Process	GO:1904861	excitatory synapse assembly	ISO	J:164563
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IGI	J:165995
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:1900454	positive regulation of long-term synaptic depression	ISO	J:164563
Biological Process	GO:0051965	positive regulation of synapse assembly	ISO	J:164563
Biological Process	GO:0060134	prepulse inhibition	IMP	J:89405
Biological Process	GO:0008104	protein localization	IDA	J:150922
Biological Process	GO:0043523	regulation of neuron apoptotic process	IMP	J:63483
Biological Process	GO:0043523	regulation of neuron apoptotic process	IGI	J:63483
Biological Process	GO:0010975	regulation of neuron projection development	IMP	J:23733
Biological Process	GO:0099151	regulation of postsynaptic density assembly	IDA	J:159100
Biological Process	GO:0099151	regulation of postsynaptic density assembly	IDA	J:159100
Biological Process	GO:0099151	regulation of postsynaptic density assembly	IMP	J:159100
Biological Process	GO:0099151	regulation of postsynaptic density assembly	IDA	J:159100
Biological Process	GO:1905606	regulation of presynapse assembly	ISO	J:155856
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:24477