GO Annotations Graph

• Symbol: Glra1
• Name: glycine receptor, alpha 1 subunit
• ID: MGI:95747

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005254	chloride channel activity	IBA	J:265628
Molecular Function	GO:0005230	extracellular ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	IMP	J:228551
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	ISO	J:155856
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	ISO	J:73065
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	IMP	J:108318
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	ISO	J:73065
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	IDA	J:20373
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	IMP	J:108318
Molecular Function	GO:0016933	extracellularly glycine-gated ion channel activity	ISO	J:155856
Molecular Function	GO:0016594	glycine binding	ISO	J:155856
Molecular Function	GO:0016594	glycine binding	IMP	J:42647
Molecular Function	GO:0016594	glycine binding	ISO	J:73065
Molecular Function	GO:0016594	glycine binding	IMP	J:20373
Molecular Function	GO:0016594	glycine binding	IDA	J:21529
Molecular Function	GO:0016594	glycine binding	IDA	J:21529
Molecular Function	GO:0016594	glycine binding	ISO	J:73065
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0030594	neurotransmitter receptor activity	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0030977	taurine binding	ISO	J:164563
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Molecular Function	GO:0022824	transmitter-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IMP	J:248717
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:248717
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0044305	calyx of Held	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0034707	chloride channel complex	IEA	J:60000
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:120269
Cellular Component	GO:0098690	glycinergic synapse	ISO	J:155856
Cellular Component	GO:0098690	glycinergic synapse	IMP	J:248717
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:248717
Cellular Component	GO:0060077	inhibitory synapse	IDA	J:77775
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:120269
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:117236
Cellular Component	GO:0016020	membrane	IDA	J:42647
Cellular Component	GO:0016020	membrane	IDA	J:1965
Cellular Component	GO:0043005	neuron projection	IDA	J:228551
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IDA	J:228551
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045211	postsynaptic membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:117236
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:112871
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:228551
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0007340	acrosome reaction	IMP	J:107699
Biological Process	GO:0007628	adult walking behavior	IMP	J:117236
Biological Process	GO:0071230	cellular response to amino acid stimulus	ISO	J:164563
Biological Process	GO:0071361	cellular response to ethanol	ISO	J:164563
Biological Process	GO:0071294	cellular response to zinc ion	ISO	J:164563
Biological Process	GO:0007268	chemical synaptic transmission	IDA	J:248717
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:105485
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:105485
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	IDA	J:248717
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:164563
Biological Process	GO:1902476	chloride transmembrane transport	IBA	J:265628
Biological Process	GO:0006821	chloride transport	ISO	J:164563
Biological Process	GO:0006821	chloride transport	ISO	J:155856
Biological Process	GO:0060080	inhibitory postsynaptic potential	IMP	J:228551
Biological Process	GO:0060080	inhibitory postsynaptic potential	IMP	J:117236
Biological Process	GO:0006820	monoatomic anion transport	ISO	J:155856
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IDA	J:248717
Biological Process	GO:0006811	monoatomic ion transport	ISO	J:164563
Biological Process	GO:0006936	muscle contraction	ISO	J:164563
Biological Process	GO:0051970	negative regulation of transmission of nerve impulse	ISO	J:164563
Biological Process	GO:0050877	nervous system process	IBA	J:265628
Biological Process	GO:0050905	neuromuscular process	IMP	J:41909
Biological Process	GO:0050905	neuromuscular process	IMP	J:41909
Biological Process	GO:0050905	neuromuscular process	IMP	J:117236
Biological Process	GO:0050884	neuromuscular process controlling posture	IMP	J:117236
Biological Process	GO:0019228	neuronal action potential	IMP	J:107942
Biological Process	GO:0019228	neuronal action potential	IMP	J:111542
Biological Process	GO:0007218	neuropeptide signaling pathway	ISO	J:164563
Biological Process	GO:0007218	neuropeptide signaling pathway	IBA	J:265628
Biological Process	GO:2000344	positive regulation of acrosome reaction	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	IBA	J:265628
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:108318
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:73065
Biological Process	GO:0042391	regulation of membrane potential	IDA	J:20373
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:108318
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	IDA	J:248717
Biological Process	GO:0043576	regulation of respiratory gaseous exchange	IMP	J:102716
Biological Process	GO:0043576	regulation of respiratory gaseous exchange	IMP	J:107942
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	IMP	J:111542
Biological Process	GO:0097305	response to alcohol	IMP	J:228551
Biological Process	GO:0060013	righting reflex	IMP	J:117236
Biological Process	GO:0001964	startle response	ISO	J:73065
Biological Process	GO:0001964	startle response	IMP	J:13547
Biological Process	GO:0001964	startle response	IMP	J:102716
Biological Process	GO:0001964	startle response	IMP	J:41909
Biological Process	GO:0001964	startle response	IMP	J:112871
Biological Process	GO:0001964	startle response	IMP	J:41909
Biological Process	GO:0001964	startle response	IMP	J:117236
Biological Process	GO:0001964	startle response	IMP	J:96481
Biological Process	GO:0001964	startle response	IMP	J:33924
Biological Process	GO:0060012	synaptic transmission, glycinergic	ISO	J:155856
Biological Process	GO:0060012	synaptic transmission, glycinergic	IMP	J:228551
Biological Process	GO:0060012	synaptic transmission, glycinergic	IMP	J:108318
Biological Process	GO:0060012	synaptic transmission, glycinergic	IMP	J:108318
Biological Process	GO:0007601	visual perception	IMP	J:117236