Fgfr3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Fgfr3
fibroblast growth factor receptor 3
MGI:95524

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:155856
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:164563
Molecular Function	GO:0017134	fibroblast growth factor binding	IBA	J:265628
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:73065
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:73065
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	ISO	J:155856
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	ISO	J:164563
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	IBA	J:265628
Molecular Function	GO:0005007	fibroblast growth factor receptor activity	IDA	J:88289
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0035198	miRNA binding	IDA	J:304938
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:76351
Molecular Function	GO:0005515	protein binding	IPI	J:156501
Molecular Function	GO:0005515	protein binding	IPI	J:110570
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72245
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	IDA	J:88289
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IDA	J:88289
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:88289
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0030133	transport vesicle	ISO	J:164563
Biological Process	GO:0061144	alveolar secondary septum development	IGI	J:50677
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0048708	astrocyte differentiation	IMP	J:81919
Biological Process	GO:0048708	astrocyte differentiation	IMP	J:81919
Biological Process	GO:0048708	astrocyte differentiation	IMP	J:81919
Biological Process	GO:0060385	axonogenesis involved in innervation	IMP	J:122378
Biological Process	GO:0060348	bone development	IMP	J:157951
Biological Process	GO:0070977	bone maturation	IMP	J:161199
Biological Process	GO:0030282	bone mineralization	IMP	J:161199
Biological Process	GO:0060349	bone morphogenesis	IMP	J:161199
Biological Process	GO:0060349	bone morphogenesis	IMP	J:151194
Biological Process	GO:0061430	bone trabecula morphogenesis	IMP	J:157951
Biological Process	GO:0055074	calcium ion homeostasis	IGI	J:201223
Biological Process	GO:0051216	cartilage development	IMP	J:99916
Biological Process	GO:0008283	cell population proliferation	IGI	J:136711
Biological Process	GO:0008283	cell population proliferation	IMP	J:96234
Biological Process	GO:0008283	cell population proliferation	IMP	J:96234
Biological Process	GO:0008283	cell population proliferation	IGI	J:136711
Biological Process	GO:0007267	cell-cell signaling	ISO	J:155856
Biological Process	GO:0022010	central nervous system myelination	IMP	J:81919
Biological Process	GO:0090102	cochlea development	IMP	J:122378
Biological Process	GO:0048546	digestive tract morphogenesis	IMP	J:151194
Biological Process	GO:0001935	endothelial cell proliferation	IMP	J:111764
Biological Process	GO:0001935	endothelial cell proliferation	IMP	J:111764
Biological Process	GO:0072148	epithelial cell fate commitment	IMP	J:151194
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:68695
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:121934
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:136711
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:157951
Biological Process	GO:1902178	fibroblast growth factor receptor apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:99916
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IDA	J:88289
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0030900	forebrain development	IMP	J:96234
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IGI	J:122387
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:117235
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:117235
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:122378
Biological Process	GO:0048839	inner ear development	IMP	J:117235
Biological Process	GO:0070307	lens fiber cell development	IGI	J:136711
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	IMP	J:68695
Biological Process	GO:0000165	MAPK cascade	IMP	J:68695
Biological Process	GO:0140014	mitotic nuclear division	IGI	J:136711
Biological Process	GO:0140014	mitotic nuclear division	IGI	J:136711
Biological Process	GO:0140014	mitotic nuclear division	IGI	J:136711
Biological Process	GO:0002009	morphogenesis of an epithelium	IMP	J:117235
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0048712	negative regulation of astrocyte differentiation	IMP	J:81919
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:96234
Biological Process	GO:0048640	negative regulation of developmental growth	IMP	J:161199
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:68695
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:121934
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IGI	J:136711
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:73065
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:157951
Biological Process	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation	IMP	J:117235
Biological Process	GO:0045839	negative regulation of mitotic nuclear division	IGI	J:136711
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	IMP	J:96234
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	IMP	J:50292
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:50292
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:50292
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:50292
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:50292
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:50292
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:50292
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:96234
Biological Process	GO:0060563	neuroepithelial cell differentiation	IMP	J:122378
Biological Process	GO:0060563	neuroepithelial cell differentiation	IMP	J:122378
Biological Process	GO:0060563	neuroepithelial cell differentiation	IMP	J:79996
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:96234
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:96234
Biological Process	GO:0014003	oligodendrocyte development	IMP	J:81919
Biological Process	GO:0038066	p38MAPK cascade	IMP	J:157951
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:88289
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0030501	positive regulation of bone mineralization	IMP	J:157951
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP	J:151194
Biological Process	GO:0045597	positive regulation of cell differentiation	TAS	J:184501
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:73065
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:153198
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	IMP	J:157951
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	IMP	J:111764
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	IBA	J:265628
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:73065
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:88289
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:68695
Biological Process	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	IGI	J:153198
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:96234
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:88289
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	ISO	J:164563
Biological Process	GO:0010518	positive regulation of phospholipase activity	ISO	J:164563
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IDA	J:88289
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:161199
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0016567	protein ubiquitination	IDA	J:88289
Biological Process	GO:0046850	regulation of bone remodeling	IMP	J:157951
Biological Process	GO:0010712	regulation of collagen metabolic process	IMP	J:157951
Biological Process	GO:0030278	regulation of ossification	IMP	J:157951
Biological Process	GO:0045670	regulation of osteoclast differentiation	IMP	J:157951
Biological Process	GO:0048678	response to axon injury	IMP	J:104421
Biological Process	GO:1904383	response to sodium phosphate	IDA	J:201223
Biological Process	GO:1904383	response to sodium phosphate	IGI	J:201223
Biological Process	GO:1904383	response to sodium phosphate	IGI	J:201223
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:151194
Biological Process	GO:0021762	substantia nigra development	IMP	J:117417
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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