Cacnb2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
MGI:894644

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	ISO	J:155856
Molecular Function	GO:0051015	actin filament binding	IDA	J:231245
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0005246	calcium channel regulator activity	ISO	J:155856
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	TAS	J:59479
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0051219	phosphoprotein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:110984
Molecular Function	GO:0005515	protein binding	IPI	J:165334
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential	ISO	J:164563
Molecular Function	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	ISO	J:164563
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IMP	J:80080
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IDA	J:80080
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IMP	J:80080
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IDA	J:80080
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:1990454	L-type voltage-gated calcium channel complex	ISO	J:164563
Cellular Component	GO:1990454	L-type voltage-gated calcium channel complex	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IMP	J:80080
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IDA	J:80080
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-525831
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9659489
Cellular Component	GO:0005891	voltage-gated calcium channel complex	ISO	J:164563
Cellular Component	GO:0005891	voltage-gated calcium channel complex	ISO	J:155856
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IBA	J:265628
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IDA	J:57712
Biological Process	GO:0070509	calcium ion import	ISO	J:164563
Biological Process	GO:0070588	calcium ion transmembrane transport	IDA	J:80080
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:80080
Biological Process	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0086045	membrane depolarization during AV node cell action potential	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0007528	neuromuscular junction development	IBA	J:265628
Biological Process	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	ISO	J:155856
Biological Process	GO:0051928	positive regulation of calcium ion transport	ISO	J:164563
Biological Process	GO:1901843	positive regulation of high voltage-gated calcium channel activity	ISO	J:155856
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	IDA	J:80080
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	ISO	J:155856
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	IBA	J:265628
Biological Process	GO:0007601	visual perception	IMP	J:80080

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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