GO Annotations Graph

• Symbol: Atp6v1e1
• Name: ATPase, H+ transporting, lysosomal V1 subunit E1
• ID: MGI:894326

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051117	ATPase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IBA	J:265628
Molecular Function	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IGI	J:76556
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:169877
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:150394
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:103213
Cellular Component	GO:0005737	cytoplasm	IDA	J:76556
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:150394
Cellular Component	GO:0005768	endosome	IDA	J:150394
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005902	microvillus	IDA	J:169877
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEA	J:72247
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	ISO	J:164563
Cellular Component	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1902600	proton transmembrane transport	IGI	J:76556
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IMP	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	EXP	J:326652