Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables proton-transporting ATPase activity, rotational mechanism. Involved in synaptic vesicle lumen acidification. Acts upstream of or within proton transmembrane transport. Located in several cellular components, including apical plasma membrane; endosome; and microvillus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIC. Orthologous to human ATP6V1E1 (ATPase H+ transporting V1 subunit E1).