GO Annotations Graph

• Symbol: Cyp19a1
• Name: cytochrome P450, family 19, subfamily a, polypeptide 1
• ID: MGI:88587

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070330	aromatase activity	ISO	J:164563
Molecular Function	GO:0070330	aromatase activity	ISO	J:155856
Molecular Function	GO:0020037	heme binding	ISO	J:164563
Molecular Function	GO:0005506	iron ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	IEA	J:72247
Molecular Function	GO:0004497	monooxygenase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	J:72247
Molecular Function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	ISO	J:155856
Molecular Function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IDA	J:26907
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0006710	androgen catabolic process	ISO	J:164563
Biological Process	GO:0008209	androgen metabolic process	ISO	J:155856
Biological Process	GO:0008209	androgen metabolic process	IMP	J:70204
Biological Process	GO:0008207	C21-steroid hormone metabolic process	ISO	J:155856
Biological Process	GO:0097720	calcineurin-mediated signaling	ISO	J:155856
Biological Process	GO:0006703	estrogen biosynthetic process	ISO	J:155856
Biological Process	GO:0030540	female genitalia development	IMP	J:48086
Biological Process	GO:0008585	female gonad development	IMP	J:48086
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0030879	mammary gland development	IMP	J:48086
Biological Process	GO:0045779	negative regulation of bone resorption	ISO	J:155856
Biological Process	GO:0002677	negative regulation of chronic inflammatory response	IMP	J:216958
Biological Process	GO:0010760	negative regulation of macrophage chemotaxis	IMP	J:216958
Biological Process	GO:2000866	positive regulation of estradiol secretion	ISO	J:164563
Biological Process	GO:0060736	prostate gland growth	IMP	J:109128
Biological Process	GO:0060736	prostate gland growth	IMP	J:70204
Biological Process	GO:0050803	regulation of synapse structure or activity	ISO	J:155856
Biological Process	GO:0061370	testosterone biosynthetic process	IMP	J:48086
Biological Process	GO:0060065	uterus development	IMP	J:48086