Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen and steroid hydroxylase activity. Involved in estrogen biosynthetic process. Acts upstream of or within several processes, including negative regulation of macrophage chemotaxis; reproductive structure development; and steroid metabolic process. Is active in endoplasmic reticulum. Is expressed in several structures, including 2-cell stage conceptus; 8-cell stage conceptus; central nervous system; gonad; and gonad primordium. Used to study Sjogren's syndrome and aromatase excess syndrome. Human ortholog(s) of this gene implicated in several diseases, including aromatase excess syndrome; bladder neck obstruction; esophagus adenocarcinoma; ovarian disease (multiple); and prostate disease (multiple). Orthologous to human CYP19A1 (cytochrome P450 family 19 subfamily A member 1).

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Gene Ontology Evidence Code Abbreviations:

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