GO Annotations Graph

• Symbol: Astl
• Name: astacin like metalloendopeptidase
• ID: MGI:3046414

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070001	aspartic-type peptidase activity	IDA	J:185161
Molecular Function	GO:0070002	glutamic-type peptidase activity	IDA	J:185161
Molecular Function	GO:0004222	metalloendopeptidase activity	IBA	J:265628
Molecular Function	GO:0008233	peptidase activity	IDA	J:182712
Molecular Function	GO:0005515	protein binding	IPI	J:182712
Cellular Component	GO:0060473	cortical granule	IDA	J:185161
Cellular Component	GO:0005737	cytoplasm	IDA	J:182712
Cellular Component	GO:0005886	plasma membrane	IDA	J:182712
Biological Process	GO:0007155	cell adhesion	IMP	J:182712
Biological Process	GO:0009566	fertilization	IMP	J:182712
Biological Process	GO:2000360	negative regulation of binding of sperm to zona pellucida	IDA	J:185161
Biological Process	GO:0010954	positive regulation of protein processing	IDA	J:185161
Biological Process	GO:0060468	prevention of polyspermy	IDA	J:185161