GO Annotations Graph

• Symbol: Slc17a8
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
• ID: MGI:3039629

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005254	chloride channel activity	ISO	J:155856
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0140788	L-glutamate uniporter activity	ISO	J:155856
Molecular Function	GO:0140788	L-glutamate uniporter activity	IDA	J:322974
Molecular Function	GO:0140788	L-glutamate uniporter activity	ISO	J:164563
Molecular Function	GO:0140788	L-glutamate uniporter activity	IDA	J:91392
Molecular Function	GO:0005326	neurotransmitter transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005436	sodium:phosphate symporter activity	ISO	J:164563
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0097440	apical dendrite	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0097441	basal dendrite	ISO	J:155856
Cellular Component	GO:0034707	chloride channel complex	IEA	J:60000
Cellular Component	GO:0060203	clathrin-sculpted glutamate transport vesicle membrane	TAS	Reactome:R-MMU-9664156
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	IBA	J:265628
Cellular Component	GO:0097451	glial limiting end-foot	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005771	multivesicular body	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:1990030	pericellular basket	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:237954
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:91392
Cellular Component	GO:0030672	synaptic vesicle membrane	IMP	J:200726
Cellular Component	GO:0030672	synaptic vesicle membrane	IEP	J:200726
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:200726
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:200726
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:200726
Biological Process	GO:0006821	chloride transport	IEA	J:60000
Biological Process	GO:0051938	L-glutamate import	ISO	J:155856
Biological Process	GO:0015813	L-glutamate transmembrane transport	IDA	J:322974
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:164563
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:155856
Biological Process	GO:0015813	L-glutamate transmembrane transport	IDA	J:91392
Biological Process	GO:0006820	monoatomic anion transport	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	ISO	J:164563
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	IBA	J:265628
Biological Process	GO:0006836	neurotransmitter transport	IEA	J:60000
Biological Process	GO:0055062	phosphate ion homeostasis	ISO	J:164563
Biological Process	GO:0006817	phosphate ion transport	IEA	J:60000
Biological Process	GO:0051951	positive regulation of glutamate uptake involved in transmission of nerve impulse	IMP	J:132704
Biological Process	GO:0051631	regulation of acetylcholine uptake	IMP	J:135586
Biological Process	GO:0051631	regulation of acetylcholine uptake	ISO	J:155856
Biological Process	GO:0050803	regulation of synapse structure or activity	IBA	J:265628
Biological Process	GO:0007605	sensory perception of sound	IEA	J:60000
Biological Process	GO:0006814	sodium ion transport	IEA	J:60000
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247