GO Annotations Graph

• Symbol: Shroom4
• Name: shroom family member 4
• ID: MGI:2685570

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051015	actin filament binding	IDA	J:116228
Molecular Function	GO:0045159	myosin II binding	IDA	J:116228
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:116228
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0043296	apical junction complex	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:116228
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:116228
Cellular Component	GO:0009925	basal plasma membrane	IDA	J:116228
Cellular Component	GO:0030864	cortical actin cytoskeleton	IDA	J:114885
Cellular Component	GO:0005737	cytoplasm	IDA	J:116228
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ISO	J:164563
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ISS	J:116398
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	IDA	J:116228
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0007015	actin filament organization	IDA	J:116228
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0050890	cognition	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000