GO Annotations Graph

• Symbol: Otud7b
• Name: OTU domain containing 7B
• ID: MGI:2654703

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IMP	J:194553
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IBA	J:265628
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IDA	J:84119
Molecular Function	GO:0008234	cysteine-type peptidase activity	IMP	J:194553
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	IDA	J:189983
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:211242
Molecular Function	GO:0005515	protein binding	IPI	J:194553
Molecular Function	GO:0005515	protein binding	IPI	J:189983
Molecular Function	GO:0005515	protein binding	IPI	J:194553
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:84119
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0001701	in utero embryonic development	IMP	J:240631
Biological Process	GO:0002385	mucosal immune response	IMP	J:194553
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:194553
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0032717	negative regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:211242
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	IDA	J:84119
Biological Process	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0035871	protein K11-linked deubiquitination	ISO	J:164563
Biological Process	GO:0035871	protein K11-linked deubiquitination	IBA	J:265628
Biological Process	GO:0071108	protein K48-linked deubiquitination	IMP	J:194553
Biological Process	GO:0071108	protein K48-linked deubiquitination	ISO	J:164563
Biological Process	GO:0071108	protein K48-linked deubiquitination	IBA	J:265628
Biological Process	GO:0070536	protein K63-linked deubiquitination	ISO	J:164563
Biological Process	GO:0070536	protein K63-linked deubiquitination	IBA	J:265628
Biological Process	GO:0006508	proteolysis	IEA	J:60000