Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables K63-linked polyubiquitin modification-dependent protein binding activity and cysteine-type deubiquitinase activity. Involved in mucosal immune response; negative regulation of canonical NF-kappaB signal transduction; and negative regulation of transcription by RNA polymerase II. Acts upstream of or within in utero embryonic development. Located in cytoplasm. Orthologous to human OTUD7B (OTU deubiquitinase 7B).