GO Annotations Graph

• Symbol: Sbno2
• Name: strawberry notch 2
• ID: MGI:2448490

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IBA	J:265628
Molecular Function	GO:0042393	histone binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:202853
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0030282	bone mineralization	IMP	J:202853
Biological Process	GO:0061430	bone trabecula morphogenesis	IMP	J:202853
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071348	cellular response to interleukin-11	IDA	J:223816
Biological Process	GO:0071354	cellular response to interleukin-6	ISO	J:164563
Biological Process	GO:0071354	cellular response to interleukin-6	IDA	J:223816
Biological Process	GO:0071354	cellular response to interleukin-6	IBA	J:265628
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IDA	J:223816
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:223816
Biological Process	GO:0002281	macrophage activation involved in immune response	ISO	J:164563
Biological Process	GO:0002281	macrophage activation involved in immune response	IMP	J:133009
Biological Process	GO:0002281	macrophage activation involved in immune response	IBA	J:265628
Biological Process	GO:0072674	multinuclear osteoclast differentiation	IMP	J:202853
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:133009
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0001503	ossification	IEA	J:60000
Biological Process	GO:0030316	osteoclast differentiation	IBA	J:265628
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:202853
Biological Process	GO:0072675	osteoclast fusion	IMP	J:202853
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:202853
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0050727	regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:133009
Biological Process	GO:0050727	regulation of inflammatory response	IBA	J:265628