Lrp4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Lrp4
low density lipoprotein receptor-related protein 4
MGI:2442252

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034185	apolipoprotein binding	ISO	J:155856
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:202742
Molecular Function	GO:0005515	protein binding	IPI	J:205644
Molecular Function	GO:0005515	protein binding	IPI	J:145446
Molecular Function	GO:0005515	protein binding	IPI	J:149003
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:145446
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IPI	J:205644
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IPI	J:145446
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031594	neuromuscular junction	IC	J:177552
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:144064
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:202742
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:103781
Cellular Component	GO:0044853	plasma membrane raft	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	ISO	J:164563
Biological Process	GO:0048856	anatomical structure development	IMP	J:119654
Biological Process	GO:0048856	anatomical structure development	IMP	J:119654
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0048813	dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:106811
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:119654
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:108168
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:108168
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:106811
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:119654
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:119654
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0048699	generation of neurons	IBA	J:265628
Biological Process	GO:0001942	hair follicle development	IMP	J:119654
Biological Process	GO:0001942	hair follicle development	IMP	J:119654
Biological Process	GO:0001822	kidney development	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:119654
Biological Process	GO:0001822	kidney development	IMP	J:119654
Biological Process	GO:0060173	limb development	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0050771	negative regulation of axonogenesis	IMP	J:188149
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IDA	J:160170
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IGI	J:160170
Biological Process	GO:0030279	negative regulation of ossification	ISO	J:164563
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:119654
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:119654
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IMP	J:144064
Biological Process	GO:1901631	positive regulation of presynaptic membrane organization	IDA	J:188149
Biological Process	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering	IMP	J:144064
Biological Process	GO:0097104	postsynaptic membrane assembly	IMP	J:177552
Biological Process	GO:0097105	presynaptic membrane assembly	IMP	J:177552
Biological Process	GO:0008104	protein localization	IMP	J:119654
Biological Process	GO:0008104	protein localization	IMP	J:119654
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:119654
Biological Process	GO:0043113	receptor clustering	IMP	J:119654
Biological Process	GO:0043113	receptor clustering	IMP	J:119654
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:145446
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	IMP	J:177552
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	IMP	J:188149
Biological Process	GO:0050808	synapse organization	ISO	J:155856
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	IDA	J:144064
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	IMP	J:119654
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	IMP	J:119654
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:138365
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:106811

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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