GO Annotations Graph

• Symbol: Bbs2
• Name: Bardet-Biedl syndrome 2
• ID: MGI:2135267

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:239231
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:73065
Cellular Component	GO:0034464	BBSome	IDA	J:207969
Cellular Component	GO:0034464	BBSome	ISO	J:164563
Cellular Component	GO:0034464	BBSome	IBA	J:265628
Cellular Component	GO:0034464	BBSome	IDA	J:156536
Cellular Component	GO:0034464	BBSome	IDA	J:193003
Cellular Component	GO:0034464	BBSome	IDA	J:177990
Cellular Component	GO:0034464	BBSome	ISO	J:73065
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0036064	ciliary basal body	ISO	J:164563
Cellular Component	GO:0036064	ciliary basal body	IBA	J:265628
Cellular Component	GO:0036064	ciliary basal body	ISO	J:193954
Cellular Component	GO:0060170	ciliary membrane	ISO	J:164563
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:180524
Cellular Component	GO:0005902	microvillus	IDA	J:217667
Cellular Component	GO:0031514	motile cilium	ISO	J:164563
Cellular Component	GO:0031514	motile cilium	IMP	J:132765
Cellular Component	GO:0031514	motile cilium	IBA	J:265628
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043005	neuron projection	IDA	J:217667
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032420	stereocilium	IDA	J:217667
Biological Process	GO:0030534	adult behavior	IMP	J:94467
Biological Process	GO:0014824	artery smooth muscle contraction	IMP	J:167249
Biological Process	GO:0048854	brain morphogenesis	IMP	J:128532
Biological Process	GO:0051216	cartilage development	IMP	J:194514
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0021987	cerebral cortex development	IMP	J:128532
Biological Process	GO:0060271	cilium assembly	IMP	J:132765
Biological Process	GO:0060271	cilium assembly	NAS	J:320058
Biological Process	GO:0060271	cilium assembly	IBA	J:265628
Biological Process	GO:0045444	fat cell differentiation	IEP	J:135549
Biological Process	GO:0010467	gene expression	IMP	J:146158
Biological Process	GO:0010467	gene expression	IMP	J:135832
Biological Process	GO:0010467	gene expression	IMP	J:146158
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	ISO	J:73065
Biological Process	GO:0021766	hippocampus development	IMP	J:128532
Biological Process	GO:0033210	leptin-mediated signaling pathway	IMP	J:146158
Biological Process	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway	IMP	J:146158
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:135832
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:146158
Biological Process	GO:0040015	negative regulation of multicellular organism growth	IMP	J:94467
Biological Process	GO:1905515	non-motile cilium assembly	IMP	J:194514
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:94467
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:135832
Biological Process	GO:0008104	protein localization	IMP	J:94467
Biological Process	GO:0008104	protein localization	IMP	J:181886
Biological Process	GO:0033365	protein localization to organelle	IDA	J:133334
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0060296	regulation of cilium beat frequency involved in ciliary motility	IMP	J:132765
Biological Process	GO:0044321	response to leptin	IMP	J:135832
Biological Process	GO:0007288	sperm axoneme assembly	IMP	J:94467
Biological Process	GO:0021756	striatum development	IMP	J:128532
Biological Process	GO:0042311	vasodilation	IMP	J:167249
Biological Process	GO:0007601	visual perception	ISO	J:164563