GO Annotations Graph

• Symbol: Gtf2a1
• Name: general transcription factor II A, 1
• ID: MGI:1933277

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:99784
Molecular Function	GO:0005515	protein binding	IPI	J:99784
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	ISO	J:164563
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:146223
Molecular Function	GO:0017025	TBP-class protein binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:99784
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:99784
Cellular Component	GO:0005672	transcription factor TFIIA complex	ISO	J:164563
Cellular Component	GO:0005672	transcription factor TFIIA complex	IBA	J:265628
Cellular Component	GO:0005672	transcription factor TFIIA complex	IDA	J:99784
Cellular Component	GO:0005669	transcription factor TFIID complex	ISO	J:164563
Cellular Component	GO:0097550	transcription preinitiation complex	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	ISO	J:164563
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	NAS	J:320280
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006366	transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	IEA	J:72247