GO Annotations Graph

• Symbol: H1f4
• Name: H1.4 linker histone, cluster member
• ID: MGI:1931527

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043531	ADP binding	ISO	J:155856
Molecular Function	GO:0016208	AMP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:164563
Molecular Function	GO:0032564	dATP binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IDA	J:94437
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0003690	double-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	ISO	J:155856
Molecular Function	GO:0031492	nucleosomal DNA binding	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:64732
Molecular Function	GO:0030527	structural constituent of chromatin	IMP	J:83954
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000792	heterochromatin	ISO	J:164563
Cellular Component	GO:0000786	nucleosome	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:207809
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IMP	J:83954
Biological Process	GO:0030261	chromosome condensation	IBA	J:265628
Biological Process	GO:0098532	histone H3-K27 trimethylation	IGI	J:225113
Biological Process	GO:0098532	histone H3-K27 trimethylation	IGI	J:225113
Biological Process	GO:0080182	histone H3-K4 trimethylation	IGI	J:225113
Biological Process	GO:0080182	histone H3-K4 trimethylation	IGI	J:225113
Biological Process	GO:0045910	negative regulation of DNA recombination	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:183665
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:183665
Biological Process	GO:0006334	nucleosome assembly	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:225113