Pycard GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Pycard
PYD and CARD domain containing
MGI:1931465

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070700	BMP receptor binding	ISO	J:164563
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IEA	J:72247
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:219619
Molecular Function	GO:0005138	interleukin-6 receptor binding	ISO	J:164563
Molecular Function	GO:0017024	myosin I binding	ISO	J:164563
Molecular Function	GO:0016505	peptidase activator activity involved in apoptotic process	ISO	J:66971
Molecular Function	GO:0002020	protease binding	ISO	J:155856
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:192821
Molecular Function	GO:0005515	protein binding	IPI	J:186690
Molecular Function	GO:0005515	protein binding	IPI	J:245276
Molecular Function	GO:0005515	protein binding	IPI	J:91292
Molecular Function	GO:0005515	protein binding	IPI	J:145965
Molecular Function	GO:0046983	protein dimerization activity	ISO	J:164563
Molecular Function	GO:0046983	protein dimerization activity	IMP	J:219619
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0032090	Pyrin domain binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0005523	tropomyosin binding	ISO	J:164563
Cellular Component	GO:0097169	AIM2 inflammasome complex	ISO	J:164563
Cellular Component	GO:0061702	canonical inflammasome complex	ISO	J:164563
Cellular Component	GO:0061702	canonical inflammasome complex	IBA	J:265628
Cellular Component	GO:0061702	canonical inflammasome complex	IDA	J:295244
Cellular Component	GO:0005737	cytoplasm	NAS	J:319953
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	NAS	J:158968
Cellular Component	GO:0005737	cytoplasm	ISO	J:145965
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-877385
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-877388
Cellular Component	GO:0005829	cytosol	IDA	J:66971
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IDA	J:91292
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0008385	IkappaB kinase complex	ISO	J:164563
Cellular Component	GO:0005874	microtubule	NAS	J:263129
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0072558	NLRP1 inflammasome complex	ISO	J:164563
Cellular Component	GO:0072559	NLRP3 inflammasome complex	ISO	J:164563
Cellular Component	GO:0140738	NLRP6 inflammasome complex	ISO	J:164563
Cellular Component	GO:0140738	NLRP6 inflammasome complex	IDA	J:316943
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:219619
Cellular Component	GO:0005634	nucleus	IDA	J:176441
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	IMP	J:197219
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:117613
Biological Process	GO:0002218	activation of innate immune response	IMP	J:146958
Biological Process	GO:0002218	activation of innate immune response	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:66971
Biological Process	GO:0071347	cellular response to interleukin-1	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:295244
Biological Process	GO:0051607	defense response to virus	NAS	J:158968
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IMP	J:91292
Biological Process	GO:0045087	innate immune response	IEA	J:72247
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0032611	interleukin-1 beta production	IGI	J:145965
Biological Process	GO:0032611	interleukin-1 beta production	IGI	J:145965
Biological Process	GO:0032611	interleukin-1 beta production	IGI	J:193522
Biological Process	GO:0032611	interleukin-1 beta production	IGI	J:145965
Biological Process	GO:0032611	interleukin-1 beta production	IGI	J:193522
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	ISO	J:164563
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	ISO	J:164563
Biological Process	GO:0010934	macrophage cytokine production	IGI	J:193522
Biological Process	GO:0010934	macrophage cytokine production	IGI	J:193522
Biological Process	GO:0044351	macropinocytosis	IMP	J:176441
Biological Process	GO:0001773	myeloid dendritic cell activation	ISO	J:164563
Biological Process	GO:0002277	myeloid dendritic cell activation involved in immune response	IMP	J:176441
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	ISO	J:164563
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0032688	negative regulation of interferon-beta production	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0071901	negative regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0044546	NLRP3 inflammasome complex assembly	ISO	J:164563
Biological Process	GO:0007231	osmosensory signaling pathway	NAS	J:187661
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	NAS	J:319676
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	NAS	J:320140
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	NAS	J:158968
Biological Process	GO:0030838	positive regulation of actin filament polymerization	IMP	J:176441
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	IMP	J:176441
Biological Process	GO:0002821	positive regulation of adaptive immune response	ISO	J:164563
Biological Process	GO:0002588	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	IMP	J:176441
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0032722	positive regulation of chemokine production	ISO	J:164563
Biological Process	GO:0032722	positive regulation of chemokine production	IMP	J:190277
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	ISO	J:164563
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:155856
Biological Process	GO:0002230	positive regulation of defense response to virus by host	IMP	J:146958
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:190277
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	NAS	J:257673
Biological Process	GO:0050729	positive regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	NAS	J:158968
Biological Process	GO:0050729	positive regulation of inflammatory response	IDA	J:259950
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IDA	J:259950
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	ISO	J:164563
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IDA	J:257673
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IMP	J:146958
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IGI	J:193522
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IGI	J:193522
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IMP	J:205949
Biological Process	GO:0032733	positive regulation of interleukin-10 production	ISO	J:164563
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IMP	J:176441
Biological Process	GO:0032757	positive regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IGI	J:193522
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IGI	J:193522
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0050766	positive regulation of phagocytosis	IMP	J:176441
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0050870	positive regulation of T cell activation	ISO	J:164563
Biological Process	GO:2000406	positive regulation of T cell migration	IMP	J:176441
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032729	positive regulation of type II interferon production	IMP	J:176441
Biological Process	GO:0051260	protein homooligomerization	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IEA	J:72247
Biological Process	GO:0070269	pyroptosis	NAS	J:158968
Biological Process	GO:0070269	pyroptosis	NAS	J:229325
Biological Process	GO:0070269	pyroptosis	NAS	J:319676
Biological Process	GO:0042981	regulation of apoptotic process	IMP	J:91292
Biological Process	GO:0010506	regulation of autophagy	IMP	J:212020
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:91292
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:176441
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:181354
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:193522
Biological Process	GO:2001242	regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	IMP	J:176441
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0009617	response to bacterium	IMP	J:212020
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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