GO Annotations Graph

• Symbol: Smoc2
• Name: SPARC related modular calcium binding 2
• ID: MGI:1929881

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IDA	J:84872
Molecular Function	GO:0050840	extracellular matrix binding	IBA	J:265628
Molecular Function	GO:0005539	glycosaminoglycan binding	IDA	J:139122
Molecular Function	GO:0008201	heparin binding	IBA	J:265628
Molecular Function	GO:0008201	heparin binding	IDA	J:139122
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0005604	basement membrane	IBA	J:265628
Cellular Component	GO:0005604	basement membrane	IDA	J:139122
Cellular Component	GO:0071944	cell periphery	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IEA	J:72247
Cellular Component	GO:0031012	extracellular matrix	IDA	J:139122
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005614	interstitial matrix	IDA	J:139122
Biological Process	GO:0030198	extracellular matrix organization	IBA	J:265628
Biological Process	GO:0030198	extracellular matrix organization	IDA	J:139122
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	IDA	J:139122
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	ISO	J:164563
Biological Process	GO:2001028	positive regulation of endothelial cell chemotaxis	ISO	J:164563
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	ISO	J:164563
Biological Process	GO:0035470	positive regulation of vascular wound healing	ISO	J:164563