Stk4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Stk4
serine/threonine kinase 4
MGI:1929004

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:238700
Molecular Function	GO:0005515	protein binding	IPI	J:112648
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:75789
Molecular Function	GO:0004672	protein kinase activity	ISO	J:156774
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:75789
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:75789
Cellular Component	GO:0005737	cytoplasm	IDA	J:80711
Cellular Component	GO:0005737	cytoplasm	IDA	J:134270
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:134270
Cellular Component	GO:0005634	nucleus	IDA	J:80711
Cellular Component	GO:0032991	protein-containing complex	ISO	J:156774
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IGI	J:156541
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:155001
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:155001
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:156541
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:156541
Biological Process	GO:0060706	cell differentiation involved in embryonic placenta development	IGI	J:155001
Biological Process	GO:0000902	cell morphogenesis	ISO	J:75789
Biological Process	GO:0008283	cell population proliferation	IGI	J:156541
Biological Process	GO:0008283	cell population proliferation	IGI	J:156541
Biological Process	GO:0008283	cell population proliferation	IGI	J:156541
Biological Process	GO:0008283	cell population proliferation	IGI	J:155001
Biological Process	GO:0007417	central nervous system development	IGI	J:155001
Biological Process	GO:0003157	endocardium development	IGI	J:155001
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:156541
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:0097284	hepatocyte apoptotic process	IGI	J:156541
Biological Process	GO:0097284	hepatocyte apoptotic process	IGI	J:156541
Biological Process	GO:0035329	hippo signaling	IMP	J:156531
Biological Process	GO:0035329	hippo signaling	ISO	J:164563
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035556	intracellular signal transduction	ISO	J:164563
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IGI	J:156541
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:156541
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:155001
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IGI	J:156541
Biological Process	GO:0046621	negative regulation of organ growth	IGI	J:156541
Biological Process	GO:0001841	neural tube formation	IGI	J:155001
Biological Process	GO:0035265	organ growth	IGI	J:156541
Biological Process	GO:0035265	organ growth	IGI	J:156541
Biological Process	GO:0035265	organ growth	IGI	J:156541
Biological Process	GO:0035265	organ growth	IGI	J:156541
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:156541
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IGI	J:156541
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IGI	J:184223
Biological Process	GO:1903945	positive regulation of hepatocyte apoptotic process	IGI	J:156541
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:156774
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:184223
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:156774
Biological Process	GO:1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate	IMP	J:142674
Biological Process	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0060215	primitive hemopoiesis	IGI	J:155001
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:75789
Biological Process	GO:0006606	protein import into nucleus	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	ISO	J:75789
Biological Process	GO:0050821	protein stabilization	IMP	J:156774
Biological Process	GO:0050821	protein stabilization	ISO	J:156774
Biological Process	GO:0051262	protein tetramerization	IEA	J:72247
Biological Process	GO:0060800	regulation of cell differentiation involved in embryonic placenta development	IGI	J:214531
Biological Process	GO:0043408	regulation of MAPK cascade	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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