GO Annotations Graph

• Symbol: Dusp10
• Name: dual specificity phosphatase 10
• ID: MGI:1927070

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008432	JUN kinase binding	ISO	J:164563
Molecular Function	GO:0033549	MAP kinase phosphatase activity	ISO	J:164563
Molecular Function	GO:0033549	MAP kinase phosphatase activity	IDA	J:242446
Molecular Function	GO:0033550	MAP kinase tyrosine phosphatase activity	IBA	J:265628
Molecular Function	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	IBA	J:265628
Molecular Function	GO:0048273	mitogen-activated protein kinase p38 binding	ISO	J:164563
Molecular Function	GO:0017018	myosin phosphatase activity	IEA	J:72245
Molecular Function	GO:0016791	phosphatase activity	ISO	J:164563
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IEA	J:72245
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IEA	J:72245
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	IEA	J:72247
Molecular Function	GO:0008330	protein tyrosine/threonine phosphatase activity	ISO	J:164563
Molecular Function	GO:0008330	protein tyrosine/threonine phosphatase activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0016311	dephosphorylation	ISO	J:164563
Biological Process	GO:0010633	negative regulation of epithelial cell migration	IMP	J:242446
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:242446
Biological Process	GO:1905042	negative regulation of epithelium regeneration	IDA	J:242446
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	IMP	J:242446
Biological Process	GO:0046329	negative regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0046329	negative regulation of JNK cascade	IMP	J:92104
Biological Process	GO:0043508	negative regulation of JUN kinase activity	ISO	J:164563
Biological Process	GO:0043508	negative regulation of JUN kinase activity	IBA	J:265628
Biological Process	GO:0043508	negative regulation of JUN kinase activity	IMP	J:92104
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	ISO	J:155856
Biological Process	GO:1903753	negative regulation of p38MAPK cascade	ISO	J:164563
Biological Process	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation	IDA	J:204430
Biological Process	GO:0060266	negative regulation of respiratory burst involved in inflammatory response	IMP	J:153759
Biological Process	GO:0032873	negative regulation of stress-activated MAPK cascade	IMP	J:153759
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:145866
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	ISO	J:164563
Biological Process	GO:1990264	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	ISO	J:164563
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	IDA	J:242446
Biological Process	GO:0002819	regulation of adaptive immune response	IMP	J:92104
Biological Process	GO:0090335	regulation of brown fat cell differentiation	IDA	J:204403
Biological Process	GO:0045088	regulation of innate immune response	IMP	J:92104
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:153759
Biological Process	GO:0051403	stress-activated MAPK cascade	IMP	J:153759
Biological Process	GO:0051403	stress-activated MAPK cascade	IMP	J:153759