GO Annotations Graph

• Symbol: Ehmt1
• Name: euchromatic histone methyltransferase 1
• ID: MGI:1924933

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	IPI	J:114884
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	IDA	J:97244
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IMP	J:143343
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IDA	J:97244
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0140948	histone H3K9 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	ISO	J:164563
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:143343
Molecular Function	GO:0005515	protein binding	IPI	J:170429
Molecular Function	GO:0005515	protein binding	IPI	J:293487
Molecular Function	GO:0005515	protein binding	IPI	J:207678
Molecular Function	GO:0005515	protein binding	IPI	J:213416
Molecular Function	GO:0005515	protein binding	IPI	J:114884
Molecular Function	GO:0005515	protein binding	IPI	J:97244
Molecular Function	GO:0005515	protein binding	IPI	J:159133
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	ISO	J:164563
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:97244
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:148615
Biological Process	GO:0006325	chromatin organization	ISO	J:164563
Biological Process	GO:0006306	DNA methylation	IDA	J:143343
Biological Process	GO:0006306	DNA methylation	IBA	J:265628
Biological Process	GO:0140718	facultative heterochromatin formation	IDA	J:159133
Biological Process	GO:0034968	histone lysine methylation	IEA	J:72247
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:170429
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:121427
Biological Process	GO:0018027	peptidyl-lysine dimethylation	IMP	J:97244
Biological Process	GO:0018027	peptidyl-lysine dimethylation	ISO	J:164563
Biological Process	GO:0018027	peptidyl-lysine dimethylation	IBA	J:265628
Biological Process	GO:0018026	peptidyl-lysine monomethylation	IMP	J:97244
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:207678
Biological Process	GO:0045995	regulation of embryonic development	IMP	J:97244
Biological Process	GO:0051570	regulation of histone H3-K9 methylation	IBA	J:265628