GO Annotations Graph

• Symbol: Eif4a3
• Name: eukaryotic translation initiation factor 4A3
• ID: MGI:1923731

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:0008143	poly(A) binding	ISO	J:164563
Molecular Function	GO:0043021	ribonucleoprotein complex binding	ISO	J:155856
Molecular Function	GO:0003724	RNA helicase activity	ISO	J:164563
Molecular Function	GO:0003724	RNA helicase activity	IBA	J:265628
Molecular Function	GO:0035613	RNA stem-loop binding	ISO	J:155856
Molecular Function	GO:0035368	selenocysteine insertion sequence binding	ISO	J:155856
Molecular Function	GO:0045182	translation regulator activity	ISO	J:155856
Cellular Component	GO:0071013	catalytic step 2 spliceosome	ISO	J:164563
Cellular Component	GO:0071013	catalytic step 2 spliceosome	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0035145	exon-exon junction complex	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:140901
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:155856
Cellular Component	GO:0071006	U2-type catalytic step 1 spliceosome	ISO	J:164563
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	ISO	J:164563
Biological Process	GO:0006406	mRNA export from nucleus	NAS	J:320148
Biological Process	GO:0000398	mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0090394	negative regulation of excitatory postsynaptic potential	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:1904570	negative regulation of selenocysteine incorporation	ISO	J:155856
Biological Process	GO:1904574	negative regulation of selenocysteine insertion sequence binding	ISO	J:155856
Biological Process	GO:0017148	negative regulation of translation	ISO	J:164563
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	ISO	J:164563
Biological Process	GO:0048026	positive regulation of mRNA splicing, via spliceosome	IMP	J:140901
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:140901
Biological Process	GO:0045727	positive regulation of translation	ISO	J:164563
Biological Process	GO:1902415	regulation of mRNA binding	ISO	J:155856
Biological Process	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	ISO	J:164563
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	ISO	J:155856