GO Annotations Graph

• Symbol: Asxl2
• Name: ASXL transcriptional regulator 2
• ID: MGI:1922552

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	IDA	J:189224
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:164563
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:187380
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:163018
Cellular Component	GO:0035517	PR-DUB complex	IBA	J:265628
Biological Process	GO:0007512	adult heart development	IMP	J:189224
Biological Process	GO:0009887	animal organ morphogenesis	IBA	J:265628
Biological Process	GO:0035630	bone mineralization involved in bone maturation	IMP	J:201571
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IMP	J:147372
Biological Process	GO:0007507	heart development	IMP	J:147372
Biological Process	GO:0003007	heart morphogenesis	IMP	J:213577
Biological Process	GO:0030225	macrophage differentiation	IMP	J:201571
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:189224
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:201571
Biological Process	GO:1900159	positive regulation of bone mineralization involved in bone maturation	IMP	J:201571
Biological Process	GO:0045600	positive regulation of fat cell differentiation	ISO	J:164563
Biological Process	GO:0010884	positive regulation of lipid storage	ISO	J:155856
Biological Process	GO:0045651	positive regulation of macrophage differentiation	IMP	J:201571
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IC	J:201571
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IMP	J:201571
Biological Process	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0051347	positive regulation of transferase activity	IMP	J:147372
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247