GO Annotations Graph

• Symbol: Wdr77
• Name: WD repeat domain 77
• ID: MGI:1917715

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008327	methyl-CpG binding	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	IDA	J:328106
Cellular Component	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	IDA	J:328106
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0034709	methylosome	ISO	J:164563
Cellular Component	GO:0034709	methylosome	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	NAS	J:320168
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	IMP	J:137003
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	IMP	J:137003
Biological Process	GO:0043985	histone H4-R3 methylation	NAS	J:320270
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:133577
Biological Process	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	IMP	J:137003
Biological Process	GO:0007309	oocyte axis specification	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGI	J:133577
Biological Process	GO:0048026	positive regulation of mRNA splicing, via spliceosome	NAS	J:320168
Biological Process	GO:0000209	protein polyubiquitination	IDA	J:328106
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:137003
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:137003
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:137003
Biological Process	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	IMP	J:137003
Biological Process	GO:0000387	spliceosomal snRNP assembly	NAS	J:320168
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IDA	J:328106