GO Annotations Graph

• Symbol: Wwtr1
• Name: WW domain containing transcription regulator 1
• ID: MGI:1917649

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:118816
Molecular Function	GO:0005515	protein binding	IPI	J:168163
Molecular Function	GO:0005515	protein binding	IPI	J:214515
Molecular Function	GO:0005515	protein binding	IPI	J:169049
Molecular Function	GO:0005515	protein binding	IPI	J:201302
Molecular Function	GO:0005515	protein binding	IPI	J:193329
Molecular Function	GO:0005515	protein binding	IPI	J:89484
Molecular Function	GO:0005515	protein binding	IPI	J:92367
Molecular Function	GO:0005515	protein binding	IPI	J:125326
Molecular Function	GO:0005515	protein binding	IPI	J:100164
Molecular Function	GO:0005515	protein binding	IPI	J:100164
Molecular Function	GO:0005515	protein binding	IPI	J:103937
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:118816
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:118816
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	IGI	J:100164
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:100164
Cellular Component	GO:0005737	cytoplasm	IDA	J:92367
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-2064924
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8985233
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:169049
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:144755
Cellular Component	GO:0005634	nucleus	IDA	J:92367
Cellular Component	GO:0005634	nucleus	IDA	J:144755
Cellular Component	GO:0005634	nucleus	IDA	J:103937
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:89484
Biological Process	GO:0060271	cilium assembly	IMP	J:119488
Biological Process	GO:0032835	glomerulus development	IMP	J:132020
Biological Process	GO:0003015	heart process	IMP	J:200670
Biological Process	GO:0035329	hippo signaling	ISO	J:164563
Biological Process	GO:0035329	hippo signaling	IBA	J:265628
Biological Process	GO:0060993	kidney morphogenesis	IMP	J:125326
Biological Process	GO:0048762	mesenchymal cell differentiation	IMP	J:125326
Biological Process	GO:0035264	multicellular organism growth	IMP	J:125326
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0045599	negative regulation of fat cell differentiation	ISO	J:164563
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IGI	J:100164
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:100164
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:100164
Biological Process	GO:0001649	osteoblast differentiation	IGI	J:100164
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	IMP	J:169049
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:89484
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:100164
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:103937
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:89484
Biological Process	GO:0016567	protein ubiquitination	IMP	J:219077
Biological Process	GO:0016567	protein ubiquitination	IDA	J:125326
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	IGI	J:201586
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:89484
Biological Process	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	IGI	J:201586
Biological Process	GO:0060390	regulation of SMAD protein signal transduction	ISO	J:164563
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IMP	J:125326
Biological Process	GO:0017145	stem cell division	ISO	J:164563
Biological Process	GO:0001894	tissue homeostasis	IMP	J:200670