GO Annotations Graph

• Symbol: Rnf41
• Name: ring finger protein 41
• ID: MGI:1914838

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005128	erythropoietin receptor binding	IDA	J:141681
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005135	interleukin-3 receptor binding	IDA	J:141681
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:92790
Molecular Function	GO:0005515	protein binding	IPI	J:214528
Molecular Function	GO:0005515	protein binding	IPI	J:148628
Molecular Function	GO:0005515	protein binding	IPI	J:192980
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	ISO	J:164563
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0006914	autophagy	IEA	J:60000
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:73065
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:73065
Biological Process	GO:1901525	negative regulation of mitophagy	IGI	J:214528
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:192980
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:0010498	proteasomal protein catabolic process	ISO	J:164563
Biological Process	GO:0051865	protein autoubiquitination	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	IDA	J:141681
Biological Process	GO:0016567	protein ubiquitination	IBA	J:265628
Biological Process	GO:0016567	protein ubiquitination	IDA	J:192980
Biological Process	GO:2000114	regulation of establishment of cell polarity	IDA	J:192980
Biological Process	GO:0010468	regulation of gene expression	IDA	J:192980
Biological Process	GO:0045619	regulation of lymphocyte differentiation	IDA	J:141681
Biological Process	GO:0043408	regulation of MAPK cascade	ISO	J:73065
Biological Process	GO:0045637	regulation of myeloid cell differentiation	IDA	J:141681
Biological Process	GO:0051896	regulation of protein kinase B signaling	ISO	J:73065
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	ISO	J:164563