GO Annotations Graph

• Symbol: Fbxo5
• Name: F-box protein 5
• ID: MGI:1914391

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0010997	anaphase-promoting complex binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140678	molecular function inhibitor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:94781
Molecular Function	GO:0005515	protein binding	IPI	J:94781
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:1990948	ubiquitin ligase inhibitor activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:94781
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0072687	meiotic spindle	IDA	J:94781
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005819	spindle	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0046785	microtubule polymerization	IDA	J:119087
Biological Process	GO:2000773	negative regulation of cellular senescence	ISO	J:164563
Biological Process	GO:0032876	negative regulation of DNA endoreduplication	ISO	J:164563
Biological Process	GO:0045835	negative regulation of meiotic nuclear division	IBA	J:265628
Biological Process	GO:0045835	negative regulation of meiotic nuclear division	IDA	J:94781
Biological Process	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	ISO	J:164563
Biological Process	GO:1904667	negative regulation of ubiquitin protein ligase activity	ISO	J:164563
Biological Process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	ISO	J:164563
Biological Process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	ISO	J:119087
Biological Process	GO:0001556	oocyte maturation	IDA	J:94781
Biological Process	GO:0001556	oocyte maturation	IMP	J:94781
Biological Process	GO:0070169	positive regulation of biomineral tissue development	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0060903	positive regulation of meiosis I	ISO	J:119087
Biological Process	GO:1905322	positive regulation of mesenchymal stem cell migration	ISO	J:164563
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0006275	regulation of DNA replication	ISO	J:164563
Biological Process	GO:0040020	regulation of meiotic nuclear division	IDA	J:119087
Biological Process	GO:0007346	regulation of mitotic cell cycle	IMP	J:110317
Biological Process	GO:0007088	regulation of mitotic nuclear division	IBA	J:265628
Biological Process	GO:0051225	spindle assembly	IDA	J:119087
Biological Process	GO:0007057	spindle assembly involved in female meiosis I	IDA	J:119087
Biological Process	GO:0016050	vesicle organization	IDA	J:119087