GO Annotations Graph

• Symbol: Ndc80
• Name: NDC80 kinetochore complex component
• ID: MGI:1914302

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030332	cyclin binding	IPI	J:196442
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0140483	kinetochore adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:103507
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IDA	J:144648
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	IDA	J:196442
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IDA	J:144648
Cellular Component	GO:0000776	kinetochore	IDA	J:196442
Cellular Component	GO:0031262	Ndc80 complex	ISO	J:164563
Cellular Component	GO:0031262	Ndc80 complex	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0000940	outer kinetochore	ISO	J:164563
Biological Process	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	IBA	J:265628
Biological Process	GO:0008608	attachment of spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0051298	centrosome duplication	ISO	J:144648
Biological Process	GO:0007059	chromosome segregation	ISO	J:164563
Biological Process	GO:0007059	chromosome segregation	NAS	J:320157
Biological Process	GO:0000132	establishment of mitotic spindle orientation	ISO	J:164563
Biological Process	GO:0008315	G2/MI transition of meiotic cell cycle	IDA	J:196442
Biological Process	GO:0051383	kinetochore organization	ISO	J:164563
Biological Process	GO:0051383	kinetochore organization	IMP	J:196442
Biological Process	GO:0051310	metaphase plate congression	ISO	J:164563
Biological Process	GO:0051310	metaphase plate congression	ISO	J:144648
Biological Process	GO:0007093	mitotic cell cycle checkpoint signaling	IMP	J:144648
Biological Process	GO:0000070	mitotic sister chromatid segregation	ISO	J:73065
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	NAS	J:320157
Biological Process	GO:0007052	mitotic spindle organization	ISO	J:164563
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	ISO	J:164563
Biological Process	GO:1905342	positive regulation of protein localization to kinetochore	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	IMP	J:196442
Biological Process	GO:0007057	spindle assembly involved in female meiosis I	IGI	J:196442
Biological Process	GO:0007057	spindle assembly involved in female meiosis I	IMP	J:196442