GO Annotations Graph

• Symbol: Riok3
• Name: RIO kinase 3
• ID: MGI:1914128

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0089720	caspase binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0030688	preribosome, small subunit precursor	ISO	J:164563
Cellular Component	GO:0030688	preribosome, small subunit precursor	IBA	J:265628
Biological Process	GO:1990786	cellular response to dsDNA	ISO	J:164563
Biological Process	GO:0071359	cellular response to dsRNA	ISO	J:164563
Biological Process	GO:0098586	cellular response to virus	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0030490	maturation of SSU-rRNA	ISO	J:164563
Biological Process	GO:0030490	maturation of SSU-rRNA	IBA	J:265628
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0039534	negative regulation of MDA-5 signaling pathway	ISO	J:164563
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0045089	positive regulation of innate immune response	ISO	J:164563
Biological Process	GO:0032728	positive regulation of interferon-beta production	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0042254	ribosome biogenesis	IEA	J:60000