GO Annotations Graph

• Symbol: Sfn
• Name: stratifin
• ID: MGI:1891831

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0051219	phosphoprotein binding	IPI	J:128960
Molecular Function	GO:0005515	protein binding	IPI	J:109025
Molecular Function	GO:0005515	protein binding	IPI	J:109025
Molecular Function	GO:0005515	protein binding	IDA	J:142024
Molecular Function	GO:0019901	protein kinase binding	IDA	J:64823
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:109025
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-1445145
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-1454713
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IDA	J:109025
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:203995
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	ISO	J:164563
Biological Process	GO:0031424	keratinization	IMP	J:6708
Biological Process	GO:0003334	keratinocyte development	IGI	J:203995
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:102931
Biological Process	GO:0043616	keratinocyte proliferation	IGI	J:203995
Biological Process	GO:0043616	keratinocyte proliferation	IGI	J:203995
Biological Process	GO:0043616	keratinocyte proliferation	IGI	J:116077
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	IGI	J:203995
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	IGI	J:116077
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IGI	J:203995
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IGI	J:116077
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:142024
Biological Process	GO:0030307	positive regulation of cell growth	IDA	J:109025
Biological Process	GO:0045606	positive regulation of epidermal cell differentiation	IMP	J:203995
Biological Process	GO:0046827	positive regulation of protein export from nucleus	IDA	J:128960
Biological Process	GO:0006611	protein export from nucleus	IDA	J:142024
Biological Process	GO:0010737	protein kinase A signaling	IDA	J:142024
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:64823
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IDA	J:64823
Biological Process	GO:0010482	regulation of epidermal cell division	IMP	J:203995
Biological Process	GO:0001836	release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0043588	skin development	IMP	J:102931
Biological Process	GO:0043588	skin development	IGI	J:116077
Biological Process	GO:0072089	stem cell proliferation	IGI	J:116077
Biological Process	GO:0072089	stem cell proliferation	IGI	J:203995