GO Annotations Graph

• Symbol: Tbx20
• Name: T-box 20
• ID: MGI:1888496

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:98516
Molecular Function	GO:0003677	DNA binding	IDA	J:89500
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:175199
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:89500
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:66480
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:98516
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:175199
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:101739
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:175199
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:175199
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:175199
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:190269
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:175199
Cellular Component	GO:0005634	nucleus	IDA	J:175199
Biological Process	GO:0003176	aortic valve development	IMP	J:101739
Biological Process	GO:0003180	aortic valve morphogenesis	ISO	J:164563
Biological Process	GO:0060413	atrial septum morphogenesis	ISO	J:164563
Biological Process	GO:0036302	atrioventricular canal development	IMP	J:178530
Biological Process	GO:0003171	atrioventricular valve development	IMP	J:178530
Biological Process	GO:0008015	blood circulation	IMP	J:98489
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IMP	J:98489
Biological Process	GO:0003207	cardiac chamber formation	IMP	J:98806
Biological Process	GO:0003207	cardiac chamber formation	IMP	J:169971
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	IMP	J:101739
Biological Process	GO:0003215	cardiac right ventricle morphogenesis	IMP	J:101739
Biological Process	GO:0003279	cardiac septum development	IMP	J:101739
Biological Process	GO:0001708	cell fate specification	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	IMP	J:98516
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:98806
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:98489
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:98489
Biological Process	GO:0036306	embryonic heart tube elongation	IMP	J:98806
Biological Process	GO:0003143	embryonic heart tube morphogenesis	IMP	J:98806
Biological Process	GO:0003272	endocardial cushion formation	IMP	J:101739
Biological Process	GO:0003272	endocardial cushion formation	IMP	J:178530
Biological Process	GO:0003203	endocardial cushion morphogenesis	IMP	J:98806
Biological Process	GO:0035922	foramen ovale closure	ISO	J:164563
Biological Process	GO:0001947	heart looping	IMP	J:101739
Biological Process	GO:0001947	heart looping	IBA	J:265628
Biological Process	GO:0001947	heart looping	IMP	J:98516
Biological Process	GO:0001947	heart looping	IMP	J:98806
Biological Process	GO:0014031	mesenchymal cell development	IMP	J:178530
Biological Process	GO:0097475	motor neuron migration	IMP	J:119655
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0006936	muscle contraction	IMP	J:98489
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:101739
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:98516
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:89500
Biological Process	GO:0010991	negative regulation of SMAD protein complex assembly	IDA	J:169971
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:98806
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:169971
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:101739
Biological Process	GO:0003148	outflow tract septum morphogenesis	IMP	J:101739
Biological Process	GO:0003148	outflow tract septum morphogenesis	ISO	J:164563
Biological Process	GO:0003344	pericardium morphogenesis	IMP	J:98806
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	IMP	J:178530
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IMP	J:98806
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:101739
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:98516
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IMP	J:178530
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:175199
Biological Process	GO:0003193	pulmonary valve formation	IMP	J:101739
Biological Process	GO:0060577	pulmonary vein morphogenesis	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010717	regulation of epithelial to mesenchymal transition	NAS	J:101739
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0003175	tricuspid valve development	IMP	J:101739
Biological Process	GO:0001570	vasculogenesis	IBA	J:265628
Biological Process	GO:0021524	visceral motor neuron differentiation	IMP	J:101739