GO Annotations Graph

• Symbol: Rgs14
• Name: regulator of G-protein signaling 14
• ID: MGI:1859709

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:155856
Molecular Function	GO:0005092	GDP-dissociation inhibitor activity	ISO	J:164563
Molecular Function	GO:0005092	GDP-dissociation inhibitor activity	ISO	J:155856
Molecular Function	GO:0032794	GTPase activating protein binding	IPI	J:172908
Molecular Function	GO:0032794	GTPase activating protein binding	IPI	J:175168
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	IDA	J:172908
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0005096	GTPase activator activity	TAS	J:69278
Molecular Function	GO:0030695	GTPase regulator activity	IEA	J:72247
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:172908
Molecular Function	GO:0005515	protein binding	IPI	J:172908
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005813	centrosome	IDA	J:94516
Cellular Component	GO:0005813	centrosome	ISO	J:155856
Cellular Component	GO:0005813	centrosome	IDA	J:175190
Cellular Component	GO:0005737	cytoplasm	IDA	J:172908
Cellular Component	GO:0005737	cytoplasm	IDA	J:94516
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:175190
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IDA	J:164681
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IDA	J:164681
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:263580
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263580
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:164681
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:164681
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005874	microtubule	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	IDA	J:175190
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:175190
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:94516
Cellular Component	GO:0005886	plasma membrane	IDA	J:172908
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IDA	J:164681
Cellular Component	GO:0014069	postsynaptic density	IDA	J:164681
Cellular Component	GO:0005819	spindle	IDA	J:175185
Cellular Component	GO:0005819	spindle	ISO	J:164563
Cellular Component	GO:0005819	spindle	IDA	J:94516
Cellular Component	GO:0000922	spindle pole	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	ISO	J:164563
Biological Process	GO:0051301	cell division	IBA	J:265628
Biological Process	GO:0007059	chromosome segregation	IMP	J:94516
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	TAS	J:69278
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0007612	learning	IMP	J:164681
Biological Process	GO:0007616	long-term memory	IMP	J:164681
Biological Process	GO:0060291	long-term synaptic potentiation	IDA	J:164681
Biological Process	GO:0000278	mitotic cell cycle	IMP	J:94516
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:263580
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:263580
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	IDA	J:172908
Biological Process	GO:0043407	negative regulation of MAP kinase activity	IMP	J:164681
Biological Process	GO:0009968	negative regulation of signal transduction	IEA	J:60000
Biological Process	GO:0031914	negative regulation of synaptic plasticity	IMP	J:164681
Biological Process	GO:0006913	nucleocytoplasmic transport	ISO	J:155856
Biological Process	GO:0006913	nucleocytoplasmic transport	IDA	J:175190
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	IDA	J:172908
Biological Process	GO:0050769	positive regulation of neurogenesis	ISO	J:155856
Biological Process	GO:0043620	regulation of DNA-templated transcription in response to stress	IDA	J:175190
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0006979	response to oxidative stress	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007051	spindle organization	IMP	J:94516
Biological Process	GO:0007051	spindle organization	ISO	J:164563
Biological Process	GO:0007051	spindle organization	IBA	J:265628
Biological Process	GO:0008542	visual learning	ISO	J:155856
Biological Process	GO:0010070	zygote asymmetric cell division	IMP	J:94516