GO Annotations Graph

• Symbol: Atp8b1
• Name: ATPase, class I, type 8B, member 1
• ID: MGI:1859665

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015247	aminophospholipid flippase activity	IDA	J:243537
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IBA	J:265628
Molecular Function	GO:1901612	cardiolipin binding	IDA	J:211244
Molecular Function	GO:0005319	lipid transporter activity	IMP	J:211244
Molecular Function	GO:0000287	magnesium ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0140345	phosphatidylcholine flippase activity	ISO	J:164563
Molecular Function	GO:0140346	phosphatidylserine flippase activity	ISO	J:155856
Molecular Function	GO:0005215	transporter activity	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0031526	brush border membrane	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:1990531	phospholipid-translocating ATPase complex	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:243537
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:211244
Cellular Component	GO:0032420	stereocilium	IDA	J:150079
Cellular Component	GO:0005802	trans-Golgi network	IBA	J:265628
Biological Process	GO:0015917	aminophospholipid transport	IDA	J:243537
Biological Process	GO:0045176	apical protein localization	ISO	J:164563
Biological Process	GO:0015721	bile acid and bile salt transport	IMP	J:149062
Biological Process	GO:0008206	bile acid metabolic process	IMP	J:89817
Biological Process	GO:0007030	Golgi organization	IBA	J:265628
Biological Process	GO:0060119	inner ear receptor cell development	IMP	J:150079
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0015711	organic anion transport	IMP	J:149062
Biological Process	GO:0045332	phospholipid translocation	ISO	J:164563
Biological Process	GO:0045332	phospholipid translocation	IBA	J:265628
Biological Process	GO:0015914	phospholipid transport	IEA	J:72247
Biological Process	GO:2001225	regulation of chloride transport	ISO	J:164563
Biological Process	GO:0032534	regulation of microvillus assembly	ISO	J:164563
Biological Process	GO:1903729	regulation of plasma membrane organization	IMP	J:227543
Biological Process	GO:0007605	sensory perception of sound	IMP	J:150079
Biological Process	GO:0021650	vestibulocochlear nerve formation	IMP	J:150079
Biological Process	GO:0006855	xenobiotic transmembrane transport	ISO	J:164563