GO Annotations Graph

• Symbol: Prok2
• Name: prokineticin 2
• ID: MGI:1354178

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	TAS	J:169941
Molecular Function	GO:0001664	G protein-coupled receptor binding	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0006935	chemotaxis	ISO	J:164563
Biological Process	GO:0007623	circadian rhythm	IDA	J:76640
Biological Process	GO:0060976	coronary vasculature development	TAS	J:169941
Biological Process	GO:0001935	endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0001935	endothelial cell proliferation	IBA	J:265628
Biological Process	GO:0003349	epicardium-derived cardiac endothelial cell differentiation	TAS	J:169941
Biological Process	GO:0060983	epicardium-derived cardiac vascular smooth muscle cell differentiation	TAS	J:169941
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0007218	neuropeptide signaling pathway	IEA	J:60000
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	ISO	J:164563
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0007283	spermatogenesis	ISO	J:164563
Biological Process	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	TAS	J:169941