GO Annotations Graph

• Symbol: Clnk
• Name: cytokine-dependent hematopoietic cell linker
• ID: MGI:1351468

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:277871
Molecular Function	GO:0005515	protein binding	IPI	J:76319
Molecular Function	GO:0005515	protein binding	IPI	J:131738
Molecular Function	GO:0005515	protein binding	IPI	J:58498
Molecular Function	GO:0044877	protein-containing complex binding	IPI	J:82731
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0042629	mast cell granule	IDA	J:76319
Cellular Component	GO:0032991	protein-containing complex	IMP	J:82731
Biological Process	GO:0006955	immune response	NAS	J:76319
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:0043303	mast cell degranulation	IMP	J:76319
Biological Process	GO:0032815	negative regulation of natural killer cell activation	IMP	J:91590
Biological Process	GO:0032815	negative regulation of natural killer cell activation	IMP	J:131738
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	IMP	J:131738
Biological Process	GO:0010941	regulation of cell death	IMP	J:277871
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IMP	J:76319
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IDA	J:58498