GO Annotations Graph

• Symbol: Homer1
• Name: homer scaffolding protein 1
• ID: MGI:1347345

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035256	G protein-coupled glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0035256	G protein-coupled glutamate receptor binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:249721
Molecular Function	GO:0005515	protein binding	IPI	J:314369
Molecular Function	GO:0005515	protein binding	IPI	J:281389
Molecular Function	GO:0005515	protein binding	IPI	J:251297
Molecular Function	GO:0005515	protein binding	IPI	J:249721
Molecular Function	GO:0005515	protein binding	IPI	J:101279
Molecular Function	GO:0005515	protein binding	IPI	J:101279
Molecular Function	GO:0005515	protein binding	IPI	J:101279
Molecular Function	GO:0005515	protein binding	IPI	J:78892
Molecular Function	GO:0005515	protein binding	IPI	J:101279
Molecular Function	GO:0005515	protein binding	IPI	J:133899
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Molecular Function	GO:0099186	structural constituent of postsynapse	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0031802	type 5 metabotropic glutamate receptor binding	ISO	J:155856
Cellular Component	GO:0045177	apical part of cell	IDA	J:95213
Cellular Component	GO:0030424	axon	IDA	J:201692
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0043034	costamere	IDA	J:133899
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:78892
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263483
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:263483
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:263483
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:263483
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263483
Cellular Component	GO:0016020	membrane	IDA	J:101279
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IMP	J:175650
Cellular Component	GO:0043005	neuron projection	IDA	J:184110
Cellular Component	GO:0044309	neuron spine	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:78892
Cellular Component	GO:0098794	postsynapse	IDA	J:271632
Cellular Component	GO:0098794	postsynapse	IDA	J:212431
Cellular Component	GO:0099524	postsynaptic cytosol	IDA	J:210337
Cellular Component	GO:0099524	postsynaptic cytosol	IDA	J:210337
Cellular Component	GO:0099524	postsynaptic cytosol	IDA	J:210337
Cellular Component	GO:0014069	postsynaptic density	IMP	J:175650
Cellular Component	GO:0014069	postsynaptic density	IDA	J:173402
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IDA	J:175650
Cellular Component	GO:0014069	postsynaptic density	IMP	J:173402
Cellular Component	GO:0014069	postsynaptic density	IDA	J:237681
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IDA	J:211830
Cellular Component	GO:0014069	postsynaptic density	IDA	J:201692
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0030018	Z disc	IDA	J:133899
Biological Process	GO:0048148	behavioral response to cocaine	IMP	J:96554
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	TAS	J:50718
Biological Process	GO:0051928	positive regulation of calcium ion transport	IMP	J:133899
Biological Process	GO:0035418	protein localization to synapse	ISO	J:155856
Biological Process	GO:0051262	protein tetramerization	ISO	J:155856
Biological Process	GO:0090279	regulation of calcium ion import	IMP	J:95212
Biological Process	GO:2001257	regulation of cation channel activity	IMP	J:95212
Biological Process	GO:1902950	regulation of dendritic spine maintenance	ISO	J:155856
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	IMP	J:263483
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	IDA	J:263483
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	IPI	J:263483
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	IDA	J:263483
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	IPI	J:263483
Biological Process	GO:2001256	regulation of store-operated calcium entry	IMP	J:95212
Biological Process	GO:2001256	regulation of store-operated calcium entry	IBA	J:265628
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0051592	response to calcium ion	ISO	J:164563
Biological Process	GO:0003009	skeletal muscle contraction	IMP	J:133899
Biological Process	GO:0048741	skeletal muscle fiber development	IMP	J:133899