GO Annotations Graph

• Symbol: Ajuba
• Name: ajuba LIM protein
• ID: MGI:1341886

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051015	actin filament binding	IDA	J:99454
Molecular Function	GO:0045294	alpha-catenin binding	IDA	J:99454
Molecular Function	GO:0045294	alpha-catenin binding	ISO	J:73065
Molecular Function	GO:0003682	chromatin binding	IDA	J:136087
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:131451
Molecular Function	GO:0005515	protein binding	IPI	J:183217
Molecular Function	GO:0005515	protein binding	IPI	J:245379
Molecular Function	GO:0005515	protein binding	IPI	J:99138
Molecular Function	GO:0005515	protein binding	IPI	J:55014
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:131451
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IMP	J:183217
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	ISO	J:73065
Cellular Component	GO:0005911	cell-cell junction	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:55014
Cellular Component	GO:0005925	focal adhesion	IDA	J:98248
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IDA	J:98248
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005634	nucleus	IDA	J:183217
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:136087
Cellular Component	GO:0005634	nucleus	IDA	J:148330
Cellular Component	GO:0000932	P-body	IBA	J:265628
Cellular Component	GO:0000932	P-body	ISO	J:73065
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:136087
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	J:99454
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0007010	cytoskeleton organization	IBA	J:265628
Biological Process	GO:0048041	focal adhesion assembly	IMP	J:98248
Biological Process	GO:0046474	glycerophospholipid biosynthetic process	IMP	J:99138
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IMP	J:99125
Biological Process	GO:0030032	lamellipodium assembly	IMP	J:98248
Biological Process	GO:0035195	miRNA-mediated gene silencing	ISO	J:73065
Biological Process	GO:0035331	negative regulation of hippo signaling	ISO	J:164563
Biological Process	GO:0035331	negative regulation of hippo signaling	IBA	J:265628
Biological Process	GO:0033673	negative regulation of kinase activity	IDA	J:99138
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:136087
Biological Process	GO:0031328	positive regulation of cellular biosynthetic process	IMP	J:99138
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:99125
Biological Process	GO:0033674	positive regulation of kinase activity	IDA	J:99138
Biological Process	GO:0043406	positive regulation of MAP kinase activity	IDA	J:55014
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	ISO	J:164563
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	IBA	J:265628
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:73065
Biological Process	GO:0008104	protein localization	IMP	J:99138
Biological Process	GO:0030334	regulation of cell migration	IDA	J:98248
Biological Process	GO:0030334	regulation of cell migration	IMP	J:98248
Biological Process	GO:1900037	regulation of cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:98248
Biological Process	GO:0001666	response to hypoxia	ISO	J:164563
Biological Process	GO:0001666	response to hypoxia	IBA	J:265628
Biological Process	GO:0031047	RNA-mediated gene silencing	IEA	J:60000
Biological Process	GO:0035313	wound healing, spreading of epidermal cells	IMP	J:98248