GO Annotations Graph

• Symbol: S100a6
• Name: S100 calcium binding protein A6 (calcyclin)
• ID: MGI:1339467

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	IDA	J:113706
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0015075	monoatomic ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:196123
Molecular Function	GO:0005515	protein binding	IPI	J:47153
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044548	S100 protein binding	ISO	J:164563
Molecular Function	GO:0044548	S100 protein binding	IBA	J:265628
Molecular Function	GO:0005523	tropomyosin binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IDA	J:113706
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0001726	ruffle	ISO	J:164563