GO Annotations Graph

• Symbol: Aqp3
• Name: aquaporin 3
• ID: MGI:1333777

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015267	channel activity	IEA	J:72247
Molecular Function	GO:0015254	glycerol channel activity	ISO	J:155856
Molecular Function	GO:0015254	glycerol channel activity	ISO	J:164563
Molecular Function	GO:0015254	glycerol channel activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0015166	polyol transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015204	urea transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015250	water channel activity	ISO	J:164563
Molecular Function	GO:0015250	water channel activity	ISO	J:155856
Molecular Function	GO:0015250	water channel activity	IBA	J:265628
Molecular Function	GO:0015250	water channel activity	TAS	J:65472
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:186879
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:95502
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:54490
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IDA	J:105930
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:105930
Cellular Component	GO:0005886	plasma membrane	TAS	J:65472
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:206664
Biological Process	GO:0090650	cellular response to oxygen-glucose deprivation	IDA	J:206664
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:106285
Biological Process	GO:0015793	glycerol transmembrane transport	IDA	J:161115
Biological Process	GO:0015793	glycerol transmembrane transport	ISO	J:164563
Biological Process	GO:0015793	glycerol transmembrane transport	ISO	J:155856
Biological Process	GO:0015793	glycerol transmembrane transport	IBA	J:265628
Biological Process	GO:0015791	polyol transmembrane transport	ISO	J:155856
Biological Process	GO:0002684	positive regulation of immune system process	ISO	J:164563
Biological Process	GO:0070295	renal water absorption	IMP	J:62449
Biological Process	GO:0070295	renal water absorption	IMP	J:66829
Biological Process	GO:0070295	renal water absorption	IGI	J:66829
Biological Process	GO:0032526	response to retinoic acid	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0015840	urea transport	IMP	J:110649
Biological Process	GO:0006833	water transport	ISO	J:155856
Biological Process	GO:0006833	water transport	IDA	J:161115
Biological Process	GO:0006833	water transport	ISO	J:164563
Biological Process	GO:0006833	water transport	IBA	J:265628
Biological Process	GO:0006833	water transport	IMP	J:106285
Biological Process	GO:0006833	water transport	IMP	J:95030
Biological Process	GO:0006833	water transport	TAS	J:65472
Biological Process	GO:0006833	water transport	IMP	J:110649