GO Annotations Graph

• Symbol: Slc40a1
• Name: solute carrier family 40 (iron-regulated transporter), member 1
• ID: MGI:1315204

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	IDA	J:94821
Molecular Function	GO:0042802	identical protein binding	IPI	J:245237
Molecular Function	GO:0005381	iron ion transmembrane transporter activity	IDA	J:94821
Molecular Function	GO:0005381	iron ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005381	iron ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005381	iron ion transmembrane transporter activity	IDA	J:62791
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0017046	peptide hormone binding	IPI	J:94821
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:164563
Molecular Function	GO:0017046	peptide hormone binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:245237
Molecular Function	GO:0005515	protein binding	IPI	J:167925
Molecular Function	GO:0005515	protein binding	IPI	J:163717
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	IGI	J:151027
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:124031
Cellular Component	GO:0005886	plasma membrane	IDA	J:176914
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:88420
Biological Process	GO:0006915	apoptotic process	IMP	J:98335
Biological Process	GO:0006915	apoptotic process	IMP	J:98335
Biological Process	GO:0003158	endothelium development	IMP	J:98335
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:176914
Biological Process	GO:0006879	intracellular iron ion homeostasis	ISO	J:164563
Biological Process	GO:1903988	iron ion export across plasma membrane	IDA	J:94821
Biological Process	GO:0034755	iron ion transmembrane transport	ISO	J:164563
Biological Process	GO:0034755	iron ion transmembrane transport	IBA	J:265628
Biological Process	GO:0034755	iron ion transmembrane transport	IGI	J:176914
Biological Process	GO:0006826	iron ion transport	IDA	J:62791
Biological Process	GO:0002260	lymphocyte homeostasis	IMP	J:98336
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IMP	J:89185
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IMP	J:98335
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IMP	J:157214
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:98335
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:163717
Biological Process	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron	IDA	J:203507
Biological Process	GO:0048536	spleen development	IMP	J:98335
Biological Process	GO:0060345	spleen trabecula formation	IMP	J:98335
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:163717