GO Annotations Graph

• Symbol: Kcnn4
• Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
• ID: MGI:1277957

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015269	calcium-activated potassium channel activity	ISO	J:164563
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IDA	J:82065
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IDA	J:74322
Molecular Function	GO:0005516	calmodulin binding	IBA	J:265628
Molecular Function	GO:0022894	Intermediate conductance calcium-activated potassium channel activity	ISO	J:155856
Molecular Function	GO:0022894	Intermediate conductance calcium-activated potassium channel activity	IBA	J:265628
Molecular Function	GO:0005267	potassium channel activity	IGI	J:116922
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IC	J:74322
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	ISO	J:164563
Biological Process	GO:0006884	cell volume homeostasis	IMP	J:130933
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:130933
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006820	monoatomic anion transport	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0045332	phospholipid translocation	IMP	J:130933
Biological Process	GO:0050714	positive regulation of protein secretion	IDA	J:74322
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0097623	potassium ion export across plasma membrane	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	ISO	J:155856
Biological Process	GO:0046541	saliva secretion	IGI	J:116922
Biological Process	GO:0030322	stabilization of membrane potential	ISO	J:164563