GO Annotations Graph

• Symbol: Ccnk
• Name: cyclin K
• ID: MGI:1276106

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	IBA	J:265628
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	ISO	J:48311
Molecular Function	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IEA	J:72247
Molecular Function	GO:0019901	protein kinase binding	ISO	J:73065
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	ISO	J:48311
Cellular Component	GO:0002944	cyclin K-CDK12 complex	ISO	J:73065
Cellular Component	GO:0002945	cyclin K-CDK13 complex	ISO	J:73065
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	ISO	J:73065
Biological Process	GO:0001701	in utero embryonic development	IMP	J:177489
Biological Process	GO:0044828	negative regulation by host of viral genome replication	ISO	J:164563
Biological Process	GO:2000737	negative regulation of stem cell differentiation	IMP	J:192997
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	IBA	J:265628
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	ISO	J:164563
Biological Process	GO:0009966	regulation of signal transduction	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:164563