GO Annotations Graph

• Symbol: Cbx4
• Name: chromobox 4
• ID: MGI:1195985

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:121427
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0035064	methylated histone binding	IDA	J:106925
Molecular Function	GO:0051219	phosphoprotein binding	IPI	J:44468
Molecular Function	GO:0005515	protein binding	IPI	J:44468
Molecular Function	GO:0003727	single-stranded RNA binding	IDA	J:106925
Molecular Function	GO:0032183	SUMO binding	IBA	J:265628
Molecular Function	GO:0032183	SUMO binding	ISO	J:73065
Molecular Function	GO:0032183	SUMO binding	IDA	J:161708
Molecular Function	GO:0061665	SUMO ligase activity	ISO	J:164563
Molecular Function	GO:0061665	SUMO ligase activity	IBA	J:265628
Molecular Function	GO:0019789	SUMO transferase activity	ISO	J:164563
Molecular Function	GO:0019789	SUMO transferase activity	EXP	J:125563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:162938
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:162938
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	IDA	J:162938
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4655387
Cellular Component	GO:0005634	nucleus	IDA	J:106925
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:44468
Cellular Component	GO:0031519	PcG protein complex	ISO	J:164563
Cellular Component	GO:0035102	PRC1 complex	ISO	J:164563
Cellular Component	GO:0035102	PRC1 complex	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:162938
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:44468
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:121427
Biological Process	GO:0016925	protein sumoylation	IBA	J:265628
Biological Process	GO:0016925	protein sumoylation	IMP	J:161708