GO Annotations Graph

• Symbol: Flot1
• Name: flotillin 1
• ID: MGI:1100500

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0002020	protease binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:114794
Molecular Function	GO:0005515	protein binding	IPI	J:107908
Molecular Function	GO:0005515	protein binding	IPI	J:107908
Molecular Function	GO:0005515	protein binding	IPI	J:107908
Molecular Function	GO:0005515	protein binding	IPI	J:107908
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0005901	caveola	ISO	J:73065
Cellular Component	GO:0005901	caveola	IDA	J:40485
Cellular Component	GO:0044291	cell-cell contact zone	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0008180	COP9 signalosome	ISO	J:164563
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IBA	J:265628
Cellular Component	GO:0098691	dopaminergic synapse	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:218183
Cellular Component	GO:0016600	flotillin complex	ISO	J:155856
Cellular Component	GO:0016600	flotillin complex	IDA	J:220503
Cellular Component	GO:0016600	flotillin complex	ISO	J:164563
Cellular Component	GO:0016600	flotillin complex	IDA	J:114794
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:107908
Cellular Component	GO:0016020	membrane	IDA	J:172256
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	IDA	J:149637
Cellular Component	GO:0045121	membrane raft	IDA	J:79783
Cellular Component	GO:0005815	microtubule organizing center	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:80703
Cellular Component	GO:0044853	plasma membrane raft	IDA	J:220503
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0048786	presynaptic active zone	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	IDA	J:107908
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0001931	uropod	ISO	J:164563
Biological Process	GO:0007411	axon guidance	ISO	J:73065
Biological Process	GO:0007409	axonogenesis	IMP	J:148846
Biological Process	GO:0071360	cellular response to exogenous dsRNA	ISO	J:164563
Biological Process	GO:0033227	dsRNA transport	ISO	J:164563
Biological Process	GO:0006897	endocytosis	ISO	J:73065
Biological Process	GO:0022617	extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:0044854	plasma membrane raft assembly	ISO	J:164563
Biological Process	GO:0044857	plasma membrane raft organization	ISO	J:164563
Biological Process	GO:1901890	positive regulation of cell junction assembly	IMP	J:220503
Biological Process	GO:1901890	positive regulation of cell junction assembly	ISO	J:164563
Biological Process	GO:1901890	positive regulation of cell junction assembly	IBA	J:265628
Biological Process	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	ISO	J:164563
Biological Process	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	IMP	J:220503
Biological Process	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	IBA	J:265628
Biological Process	GO:0001819	positive regulation of cytokine production	ISO	J:164563
Biological Process	GO:0045807	positive regulation of endocytosis	IMP	J:220508
Biological Process	GO:0045807	positive regulation of endocytosis	ISO	J:164563
Biological Process	GO:0045807	positive regulation of endocytosis	IBA	J:265628
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	ISO	J:164563
Biological Process	GO:0032728	positive regulation of interferon-beta production	ISO	J:164563
Biological Process	GO:1901741	positive regulation of myoblast fusion	IMP	J:220503
Biological Process	GO:1901741	positive regulation of myoblast fusion	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0032092	positive regulation of protein binding	IMP	J:220503
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0048643	positive regulation of skeletal muscle tissue development	ISO	J:164563
Biological Process	GO:0048643	positive regulation of skeletal muscle tissue development	IMP	J:220503
Biological Process	GO:0032226	positive regulation of synaptic transmission, dopaminergic	IMP	J:220508
Biological Process	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	ISO	J:164563
Biological Process	GO:0070528	protein kinase C signaling	IMP	J:220508
Biological Process	GO:0070528	protein kinase C signaling	ISO	J:164563
Biological Process	GO:0070528	protein kinase C signaling	IBA	J:265628
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:220503
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IBA	J:265628
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:107908
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0051580	regulation of neurotransmitter uptake	ISO	J:164563
Biological Process	GO:0002090	regulation of receptor internalization	ISO	J:164563
Biological Process	GO:0002090	regulation of receptor internalization	IMP	J:220508
Biological Process	GO:0002090	regulation of receptor internalization	IBA	J:265628
Biological Process	GO:0035023	regulation of Rho protein signal transduction	IMP	J:148846
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563