GO Annotations Graph

• Symbol: Hip1
• Name: huntingtin interacting protein 1
• ID: MGI:1099804

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0035612	AP-2 adaptor complex binding	ISO	J:164563
Molecular Function	GO:0035615	clathrin adaptor activity	IBA	J:265628
Molecular Function	GO:0030276	clathrin binding	ISO	J:155856
Molecular Function	GO:0030276	clathrin binding	ISO	J:164563
Molecular Function	GO:0030276	clathrin binding	ISO	J:73120
Molecular Function	GO:0030276	clathrin binding	ISO	J:73065
Molecular Function	GO:0032051	clathrin light chain binding	ISO	J:164563
Molecular Function	GO:0032051	clathrin light chain binding	IBA	J:265628
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:164563
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	IBA	J:265628
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	IBA	J:265628
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	ISO	J:164563
Molecular Function	GO:0005543	phospholipid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:84278
Molecular Function	GO:0005515	protein binding	IPI	J:119798
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0030136	clathrin-coated vesicle	ISO	J:164563
Cellular Component	GO:0030136	clathrin-coated vesicle	ISO	J:155856
Cellular Component	GO:0030136	clathrin-coated vesicle	IBA	J:265628
Cellular Component	GO:0030136	clathrin-coated vesicle	ISO	J:73120
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	ISO	J:155856
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	IBA	J:265628
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:84278
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:84278
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:84278
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:84278
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:84278
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:84278
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:84278
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:84278
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:83173
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0098793	presynapse	ISO	J:164563
Cellular Component	GO:0098793	presynapse	IBA	J:265628
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:125695
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:125695
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:83173
Biological Process	GO:0006915	apoptotic process	ISO	J:83173
Biological Process	GO:0097190	apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0048268	clathrin coat assembly	ISO	J:164563
Biological Process	GO:0048268	clathrin coat assembly	ISO	J:155856
Biological Process	GO:0048268	clathrin coat assembly	IBA	J:265628
Biological Process	GO:0048268	clathrin coat assembly	ISO	J:73120
Biological Process	GO:0072583	clathrin-dependent endocytosis	IEA	J:72247
Biological Process	GO:0006897	endocytosis	IDA	J:72637
Biological Process	GO:0006897	endocytosis	IBA	J:265628
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	ISO	J:164563
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	IMP	J:73120
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:125695
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:125695
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:83173
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IMP	J:84278
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IDA	J:84278
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IPI	J:84278
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IDA	J:84278
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IMP	J:84278
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IDA	J:84278
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IPI	J:84278
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	IDA	J:84278